ClinicalTrials.gov record
Completed Phase 1 Interventional

Temsirolimus, Dexamethasone, Mitoxantrone Hydrochloride, Vincristine Sulfate, and Pegaspargase in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma

ClinicalTrials.gov ID: NCT01403415

Public ClinicalTrials.gov record NCT01403415. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 12, 2026, 7:29 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Study of Temsirolimus in Combination With Intensive Re-induction Therapy for Children With Relapsed Acute Lymphoblastic Leukemia and Non-Hodgkin Lymphoma

Study identification

NCT ID
NCT01403415
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
National Cancer Institute (NCI)
NIH
Enrollment
13 participants

Conditions and interventions

Interventions

  • Dexamethasone Drug
  • Laboratory Biomarker Analysis Other
  • Methotrexate Drug
  • Mitoxantrone Hydrochloride Drug
  • Pegaspargase Drug
  • Pharmacological Study Other
  • Temsirolimus Drug
  • Vincristine Sulfate Drug

Drug · Other

Eligibility (public fields only)

Age range
1 Year to 21 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2011
Primary completion
Apr 30, 2015
Completion
Not listed
Last update posted
Jul 9, 2015

Started 2011

United States locations

U.S. sites
30
U.S. states
21
U.S. cities
29
Facility City State ZIP Site status
Children's Hospital of Alabama Birmingham Alabama 35233
Phoenix Childrens Hospital Phoenix Arizona 85016
Childrens Hospital of Orange County Orange California 92868
Lucile Packard Children's Hospital Stanford University Palo Alto California 94304
Rady Children's Hospital - San Diego San Diego California 92123
UCSF Medical Center-Parnassus San Francisco California 94143
Children's National Medical Center Washington D.C. District of Columbia 20010
Children's Healthcare of Atlanta - Egleston Atlanta Georgia 30322
Lurie Children's Hospital-Chicago Chicago Illinois 60611
Riley Hospital for Children Indianapolis Indiana 46202
C S Mott Children's Hospital Ann Arbor Michigan 48109
Children's Hospitals and Clinics of Minnesota - Minneapolis Minneapolis Minnesota 55404
University of Minnesota Medical Center-Fairview Minneapolis Minnesota 55455
University of Mississippi Medical Center Jackson Mississippi 39216
The Childrens Mercy Hospital Kansas City Missouri 64108
Washington University School of Medicine St Louis Missouri 63110
Columbia University Medical Center New York New York 10032
University of North Carolina at Chapel Hill Chapel Hill North Carolina 27599
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229
Rainbow Babies and Childrens Hospital Cleveland Ohio 44106
Nationwide Children's Hospital Columbus Ohio 43205
University of Oklahoma Health Sciences Center Oklahoma City Oklahoma 73104
Oregon Health and Science University Portland Oregon 97239
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104
Children's Hospital of Pittsburgh of UPMC Pittsburgh Pennsylvania 15224
Vanderbilt University/Ingram Cancer Center Nashville Tennessee 37232
UT Southwestern/Simmons Cancer Center-Dallas Dallas Texas 75390
Baylor College of Medicine Houston Texas 77030
Primary Children's Hospital Salt Lake City Utah 84113
Midwest Children's Cancer Center Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01403415, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 9, 2015 · Synced May 12, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01403415 live on ClinicalTrials.gov.

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