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Completed Phase 1 Interventional

Rituximab, Bendamustine Hydrochloride, and Lenalidomide in Treating Patients With Refractory or Relapsed Indolent Non-Hodgkin Lymphoma

ClinicalTrials.gov ID: NCT01429025

Public ClinicalTrials.gov record NCT01429025. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 29, 2026, 9:01 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Pilot/Feasibility Phase I Study of Bendamustine, Rituximab and Lenalidomide in Patients With Refractory/Relapsed Indolent NHL

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some find cancer cells and help kill them or carry cancer-killing substances to them. Others interfere with the ability of cancer cells to grow and spread. Drugs used in chemotherapy, such as bendamustine hydrochloride, also work in different ways to kill cancer cells or stop them from dividing. Lenalidomide may stop the growth of non-Hodgkin lymphoma by blocking blood flow to the cancer. Giving lenalidomide together with rituximab and bendamustine hydrochloride may kill more cancer cells. PURPOSE: This phase I trial studies the side effects and the best dose of giving lenalidomide together with rituximab and bendamustine hydrochloride in treating patients with refractory or relapsed indolent non-Hodgkin lymphoma.

Study identification

NCT ID
NCT01429025
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Enrollment
26 participants

Conditions and interventions

Interventions

Biological · Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2012
Primary completion
Oct 31, 2014
Completion
Jun 30, 2019
Last update posted
Oct 7, 2019

2012 – 2019

United States locations

U.S. sites
17
U.S. states
3
U.S. cities
6
Facility City State ZIP Site status
Medical Oncology and Hematology Associates-West Des Moines Clive Iowa 50325 —
Mercy Cancer Center-West Lakes Clive Iowa 50325 —
Iowa Methodist Medical Center Des Moines Iowa 50309 —
Iowa Oncology Research Association CCOP Des Moines Iowa 50309 —
Medical Oncology and Hematology Associates-Des Moines Des Moines Iowa 50309 —
Medical Oncology and Hematology Associates Des Moines Iowa 50314 —
Mercy Medical Center - Des Moines Des Moines Iowa 50314 —
Iowa Lutheran Hospital Des Moines Iowa 50316 —
Siouxland Hematology-Oncology Sioux City Iowa 51101-1733 —
Mercy Medical Center-Sioux City Sioux City Iowa 51104 —
St. Luke's Regional Medical Center Sioux City Iowa 51104 —
Methodist West Hospital West Des Moines Iowa 50266-7700 —
Mercy Medical Center-West Lakes West Des Moines Iowa 50266 —
Mayo Clinic Rochester Minnesota 55905 —
Mid Dakota Clinic Bismarck North Dakota 58501 —
Saint Alexius Medical Center Bismarck North Dakota 58501 —
Sanford Bismarck Medical Center Bismarck North Dakota 58501 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01429025, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 7, 2019 · Synced Sep 29, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01429025 live on ClinicalTrials.gov.

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