Observational Study of the Use of Pegloticase (KRYSTEXXA®) in Refractory Chronic Gout
Public ClinicalTrials.gov record NCT01466166. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Observational Study of the Use of KRYSTEXXA® (Pegloticase) in Adult Hyperuricemic Patients With Gout Refractory to Conventional Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary purpose of this study is to observe patients being treated with pegloticase in a standard healthcare setting in order to evaluate the frequency and severity of infusion reactions, anaphylaxis and immune complex related events. Additionally, serious adverse events associated with pegloticase therapy will be identified.
Study identification
- NCT ID
- NCT01466166
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 188 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 15, 2011 (Actual)
- Primary completion
- Jun 30, 2017 (Actual)
- Completion
- Jun 30, 2017 (Actual)
- Last update posted
- Jan 11, 2019
2011 – 2017
United States locations
- U.S. sites
- 67
- U.S. states
- 30
- U.S. cities
- 62
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Rheumatology Associates, PC | Birmingham | Alabama | 35205 | — |
| UAB Rheumatology | Birmingham | Alabama | 35294 | — |
| Saadat Ansari, MD, LLC | Huntsville | Alabama | 35801 | — |
| Medvin Clinical Research | Covina | California | 91723 | — |
| Alliance Clinical Research, LLC | Laguna Hills | California | 92653 | — |
| Advanced Medical Research, LLC | Lakewood | California | 90712 | — |
| Pacific Arthritis Care Center | Los Angeles | California | 90045 | — |
| R Srinivasan, MD, Inc | Monterey Park | California | 91754 | — |
| Brigid Freyne, MD, Inc | Murrieta | California | 92563 | — |
| Alliance Clinical Research | Poway | California | 92064 | — |
| Denver Nephrologists, PC | Denver | Colorado | 80218 | — |
| New England Research Associates, LLC | Trumbull | Connecticut | 06611 | — |
| Howard University Hospital | Washington D.C. | District of Columbia | 20060 | — |
| Washington DC Veteran's Affairs Medical Center | Washington D.C. | District of Columbia | 20422 | — |
| Bay Area Arthritis and Osteoporosis | Brandon | Florida | 33511 | — |
| Countryside Arthritis Center | Clearwater | Florida | 33761 | — |
| Science and Research Institute, Inc | Jupiter | Florida | 33458 | — |
| A & O Research Center | Miami | Florida | 33174 | — |
| Arthritis Research of Florida, Inc. | Palm Harbor | Florida | 34684 | — |
| Family Clinical Trials, LLC | Pembroke Pines | Florida | 33026 | — |
| Jedidiah Clinical Research | Tampa | Florida | 33604 | — |
| Midtown Medical Center | Tampa | Florida | 33614 | — |
| Global Research Partners & Consultants, Inc. | Calhoun | Georgia | 30701 | — |
| Arthritis Research & Treatment Center | Stockbridge | Georgia | 30281 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Diagnostic Rheumatology and Research PC | Indianapolis | Indiana | 46227 | — |
| Physicians' Clinic of Iowa, P.C. | Cedar Rapids | Iowa | 52401 | — |
| Central Kentucky Research Associates of Kentucky | Mount Sterling | Kentucky | 40353 | — |
| Research Integrity, LLC | Owensboro | Kentucky | 42303 | — |
| Horizon Research Group of Opelousas, LLC | Eunice | Louisiana | 70535 | — |
| Arthritis and Diabetes Clinic, Inc. | Monroe | Louisiana | 71203 | — |
| Walter Reed National Military Medical Center | Bethesda | Maryland | 20889-5630 | — |
| Klein & Associates MD, PA. | Hagerstown | Maryland | 21740 | — |
| The Center for Rheumatology and Bone Research | Wheaton | Maryland | 20902 | — |
| Clinical Pharmacology Study Groups | Worcester | Massachusetts | 01605 | — |
| Reliant Medical Group, Inc. | Worcester | Massachusetts | 01605 | — |
| University of Michigan Health System | Ann Arbor | Michigan | 48109-5422 | — |
| Caro Health Plaza | Caro | Michigan | 48723 | — |
| Infusion Associates | Grand Rapids | Michigan | 49525 | — |
| Justus J. Fiechtner, MD, PC | Lansing | Michigan | 48910 | — |
| Shores Rheumatology, PC | Saint Clair Shores | Michigan | 48081 | — |
| Saint Paul Rheumatology, PA | Eagan | Minnesota | 55121 | — |
| Kansas City Internal Medicine | Kansas City | Missouri | 64114 | — |
| Arthritis Medical Clinic | Las Vegas | Nevada | 89118 | — |
| Rheumatology Associates of North Jersey | Teaneck | New Jersey | 07666 | — |
| Rheumatology Associates of Long Island | Smithtown | New York | 11787 | — |
| NorthEast Rheumatology | Concord | North Carolina | 28025 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Physicians East, PA | Greenville | North Carolina | 27832 | — |
| Shanahan Rheumatology and Immunotherapy, PLLC | Raleigh | North Carolina | 27617 | — |
| Specialty Medical Clinic and Research Center | Sanford | North Carolina | 27330 | — |
| Southern Ohio Rheumatology | Portsmouth | Ohio | 45662 | — |
| Keystone Pain Institute, Ilumina Clinical Associates | Altoona | Pennsylvania | 16602 | — |
| Penn State Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Low Country Rheumatology | Charleston | South Carolina | 29406 | — |
| Acme Research L.L.C. | Orangeburg | South Carolina | 29118 | — |
| Ramesh C. Gupta, M.D. | Memphis | Tennessee | 38119 | — |
| Austin Regional Clinic | Austin | Texas | 78731 | — |
| Dr. Raj Marwah | El Paso | Texas | 79902 | — |
| Diagnostic Clinic of Houston | Houston | Texas | 77004 | — |
| Rheumatic Disease Clinical Research Center | Houston | Texas | 77004 | — |
| Arthritis Clinic of Northern Virginia, P.C. | Arlington | Virginia | 22205 | — |
| Arthritis & Osteoporosis Center of North Virginia | Manassas | Virginia | 20109 | — |
| Sentara Rheumatology Specialists | Norfolk | Virginia | 23502 | — |
| Apex Clinical Research | Kennewick | Washington | 99336 | — |
| Mountain State Clinical Research | Clarksburg | West Virginia | 26301 | — |
| Rheumatic Disease Center, LLP | Glendale | Wisconsin | 53217 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01466166, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 11, 2019 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01466166 live on ClinicalTrials.gov.