Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Completed Phase 3 Interventional Results available

Combination Treatment Study in Subjects With Tophaceous Gout With Lesinurad and Febuxostat

ClinicalTrials.gov ID: NCT01510769

Public ClinicalTrials.gov record NCT01510769. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 11, 2026, 12:08 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3 Randomized, Double-Blind, Multicenter, Placebo- Controlled, Combination Study to Evaluate the Efficacy and Safety of Lesinurad and Febuxostat Compared to Febuxostat Alone at Lowering Serum Uric Acid and Resolving Tophi in Subjects With Tophaceous Gout

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will compare the serum uric acid lowering effects, clinical benefits, and safety of lesinurad in combination with febuxostat to febuxostat alone in patients with tophaceaous gout.

Study identification

NCT ID
NCT01510769
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Ardea Biosciences, Inc.
Industry
Enrollment
330 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 31, 2011
Primary completion
May 31, 2014
Completion
May 31, 2014
Last update posted
May 25, 2016

2012 – 2014

United States locations

U.S. sites
99
U.S. states
30
U.S. cities
88
Facility City State ZIP Site status
Not listed Birmingham Alabama 35211
Not listed Goodyear Arizona 85395
Not listed Peoria Arizona 85381
Not listed Pheonix Arizona 85023
Not listed Tucson Arizona 85724
Not listed Little Rock Arkansas 72204
Not listed Little Rock Arkansas 72223
Not listed Glendale California 91204
Not listed Huntington Beach California 92646
Not listed Irvine California 92618
Not listed La Jolla California 92037
Not listed Los Angeles California 90048
Not listed Rancho Cucamonga California 91730
Not listed San Diego California 92108
Not listed Denver Colorado 80220
Not listed Denver Colorado 80230
Not listed Englewood Colorado 80113
Not listed Trumball Connecticut 06611
Not listed Washington D.C. District of Columbia 20422
Not listed Boynton Beach Florida 33472
Not listed Brooksville Florida 34601
Not listed East Brandenton Florida 34208
Not listed Fleming Island Florida 32003
Not listed Miami Florida 33135
Not listed Napels Florida 34102
Not listed Pembroke Pines Florida 33027
Not listed Pembroke Pines Florida 33029
Not listed Port Orange Florida 32127
Not listed Tampa Florida 33606
Not listed Tampa Florida 33607
Not listed Tampa Florida 33614
Not listed Vero Beach Florida 32960
Not listed Winter Haven Florida 33880
Not listed Conyers Georgia 30013
Not listed Johns Creek Georgia 30097
Not listed Newnan Georgia 30265
Not listed Savannah Georgia 31406
Not listed Honolulu Hawaii 96814
Not listed Meridian Idaho 83642
Not listed Meridian Idaho 83646
Not listed Chicago Illinois 60624
Not listed Chicago Illinois 60637
Not listed Gurnee Illinois 60031
Not listed Springfield Illinois 62704
Not listed Springfield Illinois 62711
Not listed Elizabethtown Kentucky 42701
Not listed Lexington Kentucky 40504
Not listed Frederick Maryland 21702
Not listed Kalamazoo Michigan 49009
Not listed Southfield Michigan 48034
Not listed Jackson Mississippi 39202
Not listed Olive Branch Mississippi 38654
Not listed Jefferson City Missouri 65109
Not listed St Louis Missouri 63117
Not listed Missoula Montana 59808
Not listed Mineola New York 11501
Not listed New York New York 10016
Not listed Calabash North Carolina 28467
Not listed Durham North Carolina 27710
Not listed Greenville North Carolina 27834
Not listed Wilmington North Carolina 28401
Not listed Winston-Salem North Carolina 27103
Not listed Fargo North Dakota 58103
Not listed Columbus Ohio 43203
Not listed Middleburg Ohio 44130
Not listed Wadsworth Ohio 44281
Not listed Oklahoma City Oklahoma 73103
Not listed Oklahoma City Oklahoma 73112
Not listed Belle Vernon Pennsylvania 15012
Not listed Clairton Pennsylvania 15025
Not listed Duncansville Pennsylvania 16635
Not listed Jenkintown Pennsylvania 19046
Not listed Lansdale Pennsylvania 19446
Not listed Pittsburgh Pennsylvania 15206
Not listed Scottdale Pennsylvania 15683
Not listed Sellersville Pennsylvania 18960
Not listed Columbia South Carolina 29204
Not listed Greenville South Carolina 29615
Not listed Mt. Pleasant South Carolina 29464
Not listed Spartanburg South Carolina 29303
Not listed Jackson Tennessee 38305
Not listed Memphis Tennessee 38119
Not listed Austin Texas 78705
Not listed Austin Texas 78758
Not listed Corpus Christi Texas 78413
Not listed Dallas Texas 75218
Not listed Houston Texas 77004
Not listed Houston Texas 77074
Not listed San Antonio Texas 78229
Not listed Sugar Land Texas 77479
Not listed Victoria Texas 77901
Not listed Waco Texas 76708
Not listed Chesapeake Virginia 23320
Not listed Danville Virginia 24541
Not listed Richmond Virginia 23235
Not listed Suffolk Virginia 23435
Not listed Virginia Beach Virginia 23462
Not listed Seattle Washington 98104
Not listed Morgantown West Virginia 26505

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 25 non-U.S. sites.

Recently updated Tophaceous Gout trials

Other public records listing Tophaceous Gout. Sorted by last update posted; newest first. Not a recommendation.

All Tophaceous Gout trials →

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01510769, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 25, 2016 · Synced Sep 11, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01510769 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →