Study to Assess the Clinical Efficacy and Safety of Intravitreal Aflibercept Injection (IAI;EYLEA®;BAY86-5321) in Patients With Branch Retinal Vein Occlusion (BRVO)
Public ClinicalTrials.gov record NCT01521559. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-Masked, Randomized, Active-Controlled Study of the Efficacy, Safety, and Tolerability of Intravitreal Administration of VEGF Trap-Eye (Intravitreal Aflibercept Injection [IAI]) in Patients With Macular Edema Secondary to Branch Retinal Vein Occlusion
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a phase III, double-masked, randomized, active-controlled, parallel-group, 52-week study to assess the efficacy and safety of Intravitreal Aflibercept Injection (IAI;EYLEA®;BAY86-5321) compared to laser treatment in patients with macular edema secondary to BRVO.
Study identification
- NCT ID
- NCT01521559
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 183 participants
Conditions and interventions
Conditions
Interventions
- Macular Laser Photocoagulation Procedure
- Intravitreal Aflibercept Injection (IAI;EYLEA®;BAY86-5321) Drug
Procedure · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2012 (Type not available)
- Primary completion
- Aug 2013 (Actual)
- Completion
- Mar 2014 (Actual)
- Last update posted
- Nov 13, 2014
2012 – 2014
United States locations
- U.S. sites
- 45
- U.S. states
- 24
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Phoenix | Arizona | — | — |
| Not listed | Tucson | Arizona | — | — |
| Not listed | Beverly Hills | California | — | — |
| Not listed | La Jolla | California | — | — |
| Not listed | Mountain View | California | — | — |
| Not listed | Palm Desert | California | — | — |
| Not listed | Sacramento | California | — | — |
| Not listed | Colorado Springs | Colorado | — | — |
| Not listed | Fort Myers | Florida | — | — |
| Not listed | Miami | Florida | — | — |
| Not listed | Plantation | Florida | — | — |
| Not listed | Stuart | Florida | — | — |
| Not listed | Tampa | Florida | — | — |
| Not listed | Winter Haven | Florida | — | — |
| Not listed | Augusta | Georgia | — | — |
| Not listed | Chicago | Illinois | — | — |
| Not listed | Baltimore (2 Locations) | Maryland | — | — |
| Not listed | Hagerstown | Maryland | — | — |
| Not listed | Boston (2 Locations) | Massachusetts | — | — |
| Not listed | Grand Rapids | Michigan | — | — |
| Not listed | Jackson | Michigan | — | — |
| Not listed | Southfield | Michigan | — | — |
| Not listed | Florissant | Missouri | — | — |
| Not listed | Lincoln | Nebraska | — | — |
| Not listed | Las Vegas | Nevada | — | — |
| Not listed | Teaneck | New Jersey | — | — |
| Not listed | Orchard Park | New York | — | — |
| Not listed | Syracuse | New York | — | — |
| Not listed | Charlotte | North Carolina | — | — |
| Not listed | Oklahoma City | Oklahoma | — | — |
| Not listed | Portland | Oregon | — | — |
| Not listed | Kingston | Pennsylvania | — | — |
| Not listed | West Mifflin | Pennsylvania | — | — |
| Not listed | Florence | South Carolina | — | — |
| Not listed | Ladson | South Carolina | — | — |
| Not listed | West Columbia | South Carolina | — | — |
| Not listed | Rapid City | South Dakota | — | — |
| Not listed | Nashville | Tennessee | — | — |
| Not listed | Abilene | Texas | — | — |
| Not listed | Fort Worth | Texas | — | — |
| Not listed | Harlingen | Texas | — | — |
| Not listed | Houston | Texas | — | — |
| Not listed | San Antonio | Texas | — | — |
| Not listed | Seattle | Washington | — | — |
| Not listed | Milwaukee | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01521559, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 13, 2014 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01521559 live on ClinicalTrials.gov.