ClinicalTrials.gov record
Completed Phase 3 Interventional Results available

Study to Assess the Clinical Efficacy and Safety of Intravitreal Aflibercept Injection (IAI;EYLEA®;BAY86-5321) in Patients With Branch Retinal Vein Occlusion (BRVO)

ClinicalTrials.gov ID: NCT01521559

Public ClinicalTrials.gov record NCT01521559. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 6, 2026, 8:38 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Double-Masked, Randomized, Active-Controlled Study of the Efficacy, Safety, and Tolerability of Intravitreal Administration of VEGF Trap-Eye (Intravitreal Aflibercept Injection [IAI]) in Patients With Macular Edema Secondary to Branch Retinal Vein Occlusion

Study identification

NCT ID
NCT01521559
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Regeneron Pharmaceuticals
Industry
Enrollment
183 participants

Conditions and interventions

Interventions

  • Intravitreal Aflibercept Injection (IAI;EYLEA®;BAY86-5321) Drug
  • Macular Laser Photocoagulation Procedure

Drug · Procedure

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2012
Primary completion
Jul 31, 2013
Completion
Feb 28, 2014
Last update posted
Nov 12, 2014

2012 – 2014

United States locations

U.S. sites
45
U.S. states
24
U.S. cities
45
Facility City State ZIP Site status
Not listed Phoenix Arizona
Not listed Tucson Arizona
Not listed Beverly Hills California
Not listed La Jolla California
Not listed Mountain View California
Not listed Palm Desert California
Not listed Sacramento California
Not listed Colorado Springs Colorado
Not listed Fort Myers Florida
Not listed Miami Florida
Not listed Plantation Florida
Not listed Stuart Florida
Not listed Tampa Florida
Not listed Winter Haven Florida
Not listed Augusta Georgia
Not listed Chicago Illinois
Not listed Baltimore (2 Locations) Maryland
Not listed Hagerstown Maryland
Not listed Boston (2 Locations) Massachusetts
Not listed Grand Rapids Michigan
Not listed Jackson Michigan
Not listed Southfield Michigan
Not listed Florissant Missouri
Not listed Lincoln Nebraska
Not listed Las Vegas Nevada
Not listed Teaneck New Jersey
Not listed Orchard Park New York
Not listed Syracuse New York
Not listed Charlotte North Carolina
Not listed Oklahoma City Oklahoma
Not listed Portland Oregon
Not listed Kingston Pennsylvania
Not listed West Mifflin Pennsylvania
Not listed Florence South Carolina
Not listed Ladson South Carolina
Not listed West Columbia South Carolina
Not listed Rapid City South Dakota
Not listed Nashville Tennessee
Not listed Abilene Texas
Not listed Fort Worth Texas
Not listed Harlingen Texas
Not listed Houston Texas
Not listed San Antonio Texas
Not listed Seattle Washington
Not listed Milwaukee Wisconsin

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01521559, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 12, 2014 · Synced May 6, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01521559 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →