ClinicalTrials.gov record
Completed Phase 2 Interventional Results available

Ofatumumab in Combination With Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine Sulfate, and Dexamethasone Alternating With Ofatumumab in Combination With Cytarabine and Methotrexate in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma

ClinicalTrials.gov ID: NCT01527149

Public ClinicalTrials.gov record NCT01527149. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 16, 2026, 7:57 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Ofatumumab (O) in Combination With Chemotherapy: Hyper-Fractionated Cyclophosphamide, Doxorubicin, Vincristine and Dexamethasone (O-HyperCVAD) Alternating With Ofatumumab High-Dose Cytarabine and Methotrexate (O-MA) for Patients With Newly Diagnosed Mantle Cell Lymphoma

Study identification

NCT ID
NCT01527149
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Roswell Park Cancer Institute
Other
Enrollment
37 participants

Conditions and interventions

Interventions

  • Autologous Hematopoietic Stem Cell Transplantation Procedure
  • Cyclophosphamide Drug
  • Cytarabine Drug
  • Dexamethasone Drug
  • Doxorubicin Hydrochloride Drug
  • Laboratory Biomarker Analysis Other
  • Methotrexate Drug
  • Ofatumumab Biological
  • Vincristine Sulfate Drug

Procedure · Drug · Other + 1 more

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 5, 2011
Primary completion
Apr 25, 2018
Completion
Jan 10, 2024
Last update posted
Feb 6, 2024

2011 – 2024

United States locations

U.S. sites
2
U.S. states
2
U.S. cities
2
Facility City State ZIP Site status
Roswell Park Cancer Institute Buffalo New York 14263
Vanderbilt University/Ingram Cancer Center Nashville Tennessee 37232

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01527149, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 6, 2024 · Synced May 16, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01527149 live on ClinicalTrials.gov.

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