Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction
Public ClinicalTrials.gov record NCT01638533. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1 and Pharmacokinetic Single Agent Study of Romidepsin in Patients With, Lymphomas, Chronic Lymphocytic Leukemia, and Select Solid Tumors and Varying Degrees of Liver Dysfunction
Study identification
- NCT ID
- NCT01638533
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- National Cancer Institute (NCI)
- NIH
- Enrollment
- 37 participants
Conditions and interventions
Conditions
- Glioma
- Hematopoietic and Lymphoid Cell Neoplasm
- Lymphoma
- Metastatic Malignant Solid Neoplasm
- Neuroendocrine Neoplasm
- Recurrent Adult Soft Tissue Sarcoma
- Recurrent Bladder Carcinoma
- Recurrent Breast Carcinoma
- Recurrent Chronic Lymphocytic Leukemia
- Recurrent Colorectal Carcinoma
- Recurrent Head and Neck Carcinoma
- Recurrent Lung Carcinoma
- Recurrent Malignant Solid Neoplasm
- Recurrent Melanoma
- Recurrent Pancreatic Carcinoma
- Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
- Recurrent Prostate Carcinoma
- Recurrent Renal Cell Carcinoma
- Recurrent Thyroid Gland Carcinoma
- Refractory Chronic Lymphocytic Leukemia
- Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma
- Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
- Stage III Breast Cancer AJCC v7
- Stage III Colorectal Cancer AJCC v7
- Stage III Cutaneous Melanoma AJCC v7
- Stage III Lung Cancer AJCC v7
- Stage III Pancreatic Cancer AJCC v6 and v7
- Stage III Prostate Cancer AJCC v7
- Stage III Renal Cell Cancer AJCC v7
- Stage III Soft Tissue Sarcoma AJCC v7
- Stage IIIA Breast Cancer AJCC v7
- Stage IIIA Colorectal Cancer AJCC v7
- Stage IIIA Cutaneous Melanoma AJCC v7
- Stage IIIB Breast Cancer AJCC v7
- Stage IIIB Colorectal Cancer AJCC v7
- Stage IIIB Cutaneous Melanoma AJCC v7
- Stage IIIC Breast Cancer AJCC v7
- Stage IIIC Colorectal Cancer AJCC v7
- Stage IIIC Cutaneous Melanoma AJCC v7
- Stage IV Breast Cancer AJCC v6 and v7
- Stage IV Colorectal Cancer AJCC v7
- Stage IV Cutaneous Melanoma AJCC v6 and v7
- Stage IV Lung Cancer AJCC v7
- Stage IV Pancreatic Cancer AJCC v6 and v7
- Stage IV Prostate Cancer AJCC v7
- Stage IV Renal Cell Cancer AJCC v7
- Stage IV Soft Tissue Sarcoma AJCC v7
- Stage IVA Colorectal Cancer AJCC v7
- Stage IVB Colorectal Cancer AJCC v7
- Unresectable Solid Neoplasm
Interventions
- Pharmacological Study Other
- Romidepsin Drug
Other · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2, 2012
- Primary completion
- Nov 28, 2018
- Completion
- Aug 31, 2020
- Last update posted
- Feb 6, 2025
2012 – 2020
United States locations
- U.S. sites
- 11
- U.S. states
- 8
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010 | — |
| University of California Davis Comprehensive Cancer Center | Sacramento | California | 95817 | — |
| Emory University Hospital/Winship Cancer Institute | Atlanta | Georgia | 30322 | — |
| University of Chicago Comprehensive Cancer Center | Chicago | Illinois | 60637 | — |
| Johns Hopkins University/Sidney Kimmel Cancer Center | Baltimore | Maryland | 21287 | — |
| National Cancer Institute Developmental Therapeutics Clinic | Bethesda | Maryland | 20892 | — |
| Wayne State University/Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Mayo Clinic in Rochester | Rochester | Minnesota | 55905 | — |
| Case Western Reserve University | Cleveland | Ohio | 44106 | — |
| Penn State Milton S Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01638533, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 6, 2025 · Synced May 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01638533 live on ClinicalTrials.gov.