ClinicalTrials.gov record
Completed Phase 3 Interventional

A Study of Onartuzumab in Combination With mFOLFOX6 in Participants With Metastatic HER2-Negative and MET-Positive Gastroesophageal Cancer

ClinicalTrials.gov ID: NCT01662869

Public ClinicalTrials.gov record NCT01662869. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 29, 2026, 12:17 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Phase III, Multicenter, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Onartuzumab (MetMAb) in Combination With 5-Fluorouracil, Folinic Acid, and Oxaliplatin (mFOLFOX6) in Patients With Metastatic HER2-Negative, MET-Positive Gastroesophageal Cancer

Study identification

NCT ID
NCT01662869
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
564 participants

Conditions and interventions

Conditions

Interventions

  • 5-Fluoruracil Drug
  • Folinic acid Drug
  • Onartuzumab Drug
  • Oxaliplatin Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 31, 2012
Primary completion
Nov 30, 2015
Completion
Nov 30, 2015
Last update posted
Nov 1, 2016

2012 – 2015

United States locations

U.S. sites
15
U.S. states
11
U.S. cities
14
Facility City State ZIP Site status
Not listed Los Angeles California 90095
Not listed Denver Colorado 80218
Not listed Fort Myers Florida 33908
Not listed St. Petersburg Florida 33705
Not listed Chicago Illinois 60637
Not listed Albany New York 12206
Not listed New York New York 10065
Not listed Durham North Carolina 27710
Not listed Cincinnati Ohio 45219
Not listed Providence Rhode Island 02903
Not listed Providence Rhode Island 02906
Not listed Nashville Tennessee 37203
Not listed Austin Texas 78731
Not listed Tyler Texas 75702
Not listed Vancouver Washington 98684

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 110 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01662869, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 1, 2016 · Synced Apr 29, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01662869 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →