ClinicalTrials.gov record
Completed Phase 2 Interventional Results available

Trebananib With or Without Bevacizumab, Pazopanib Hydrochloride, Sorafenib Tosylate, or Sunitinib Malate in Treating Patients With Advanced Kidney Cancer

ClinicalTrials.gov ID: NCT01664182

Public ClinicalTrials.gov record NCT01664182. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 3, 2026, 10:10 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Phase 2 Study of AMG 386 With or Without Continued Anti-Vascular Endothelial Growth Factor (VEGF) Therapy in Patients With Renal Cell Carcinoma Who Have Progressed on Bevacizumab, Pazopanib, Sorafenib, or Sunitinib

Study identification

NCT ID
NCT01664182
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
National Cancer Institute (NCI)
NIH
Enrollment
41 participants

Conditions and interventions

Interventions

  • Bevacizumab Biological
  • Pazopanib Hydrochloride Drug
  • Sorafenib Tosylate Drug
  • Sunitinib Malate Drug
  • Trebananib Biological

Biological · Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 31, 2012
Primary completion
Dec 6, 2020
Completion
Dec 6, 2020
Last update posted
Jun 6, 2022

2012 – 2020

United States locations

U.S. sites
12
U.S. states
7
U.S. cities
12
Facility City State ZIP Site status
City of Hope Comprehensive Cancer Center Duarte California 91010
USC / Norris Comprehensive Cancer Center Los Angeles California 90033
University of California Davis Comprehensive Cancer Center Sacramento California 95817
City of Hope South Pasadena South Pasadena California 91030
Wayne State University/Karmanos Cancer Institute Detroit Michigan 48201
Mayo Clinic in Rochester Rochester Minnesota 55905
Metro Minnesota Community Oncology Research Consortium Saint Louis Park Minnesota 55416
Rutgers Cancer Institute of New Jersey New Brunswick New Jersey 08903
UNC Lineberger Comprehensive Cancer Center Chapel Hill North Carolina 27599
Penn State Milton S Hershey Medical Center Hershey Pennsylvania 17033-0850
University of Pittsburgh Cancer Institute (UPCI) Pittsburgh Pennsylvania 15232
VCU Massey Cancer Center at Hanover Medical Park Mechanicsville Virginia 23116

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01664182, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 6, 2022 · Synced May 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01664182 live on ClinicalTrials.gov.

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