ClinicalTrials.gov record
Efficacy and Safety Study With Diltiazem Hydrochloride Cream to Treat Anal Fissures
ClinicalTrials.gov ID: NCT01690221
Public ClinicalTrials.gov record NCT01690221. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced Apr 22, 2026, 11:18 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3B, Randomized, Double-Blind, Placebo-Controlled, Parallel-Treatment Group, Multicenter Efficacy and Safety Study of Topical Diltiazem Hydrochloride 2% Cream in Subjects With Anal Fissure
Study identification
- NCT ID
- NCT01690221
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Ventrus Biosciences, Inc
- Industry
- Enrollment
- 434 participants
Conditions and interventions
Conditions
Interventions
- Placebo Drug
- VEN 307 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 30, 2012
- Primary completion
- Nov 30, 2013
- Completion
- Dec 31, 2013
- Last update posted
- Jan 22, 2014
2012 – 2014
United States locations
- U.S. sites
- 103
- U.S. states
- 34
- U.S. cities
- 88
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Crawford Clinic | Anniston | Alabama | 36207 | — |
| Surgical Association of Mobile | Mobile | Alabama | 36607 | — |
| University of South Alabama | Mobile | Alabama | 36617 | — |
| Montgomery Women's Health Association, PC | Montgomery | Alabama | 36117 | — |
| Mayo Clinic - Arizona | Phoenix | Arizona | 85054 | — |
| Desert Sun Clinical Research, LLC | Tucson | Arizona | 85710 | — |
| Arrowhead Regional Medical Center | Colton | California | 92324 | — |
| UC San Diego | La Jolla | California | 92093 | — |
| Alliance Research Centers | Laguna Hills | California | 92653 | — |
| Axis Clinical Trials | Los Angeles | California | 90036 | — |
| Cedars Sinai | Los Angeles | California | 90048 | — |
| Gastrointestinal Biosciences | Los Angeles | California | 90067 | — |
| University of California - Irvine Medical Center | Orange | California | 92868 | — |
| Digestive Care Associated, A Medical Corporation | San Carlos | California | 94070 | — |
| West Coast Clinical Research | Tarzana | California | 91356 | — |
| Rocky Mountain Clinical Research, LLC | Denver | Colorado | 80229 | — |
| Colorado Research Works | Pueblo | Colorado | 81008 | — |
| Rocky Mountain Clinical Research, LLC | Thornton | Colorado | 80229 | — |
| Connecticut Clinical Research Foundation CT Gastroenterology Institute At Bristol Hospital | Bristol | Connecticut | 06010 | — |
| Washington Hospital Center - MedStar Health Research Institute | Washington D.C. | District of Columbia | 20010 | — |
| Innovative Medical Research of South Florida | Aventura | Florida | 33160 | — |
| South Lake Pain Institute | Clermont | Florida | 34711 | — |
| Private Practice | Hollywood | Florida | 33021 | — |
| Advance Medical Research Center | Miami | Florida | 33135 | — |
| Well Pharma Medical Research Corp. | Miami | Florida | 33143 | — |
| Akta Medika | Miami Beach | Florida | 33140 | — |
| Gastroenterology Group of Naples, PA | Naples | Florida | 34102 | — |
| Healthcare Clinical Data, Inc. | North Miami | Florida | 33161 | — |
| Private Practice | Pembroke Pines | Florida | 33024 | — |
| Advanced Medical Research Center | Port Orange | Florida | 32127 | — |
| University of South Florida, South Campus | Tampa | Florida | 33606 | — |
| Florida Medical Clinic, P.A. | Zephyrhills | Florida | 33542 | — |
| Morehouse School of Medicine | Atlanta | Georgia | 30310 | — |
| Georgia Health Sciences University | Augusta | Georgia | 30912 | — |
| Atlanta Center for Gastroenterology | Decatur | Georgia | 30033 | — |
| Gastrointestinal Specialist of Georgia | Marietta | Georgia | 30060 | — |
| Atlanta Gastroenterology Consultants | Suwanee | Georgia | 30024 | — |
| NCH Medical Group | Arlington Heights | Illinois | 60004 | — |
| North Shore University Health System | Evanston | Illinois | 60201 | — |
| Indiana University School of Medicine | Indianapolis | Indiana | 46202 | — |
| Kendrick Regional Medical Center | Indianapolis | Indiana | 46237 | — |
| University of Iowa Hospital and Clinics | Iowa City | Iowa | 52242 | — |
| University of Louisville | Louisville | Kentucky | 40202-1622 | — |
| Delta Research Partners | Monroe | Louisiana | 71201 | — |
| Ochsner | New Orleans | Louisiana | 70121 | — |
| Investigative Clinical Research | Annapolis | Maryland | 21401 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Metropolitan Gastroenterology Group, Chevy Chase Clinical Research | Chevy Chase | Maryland | 20815 | — |
| Gastro Center of Maryland | Columbia | Maryland | 21045 | — |
| Meritus Center For Clinical Research | Hagerstown | Maryland | 21742 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Baystate Medical Center Department of Surgery | Springfield | Massachusetts | 01199 | — |
| Center for Digestive Health | Troy | Michigan | 48098 | — |
| CRC of Jackson | Jackson | Mississippi | 39202 | — |
| Jefferson City Medical Group | Jefferson City | Missouri | 65109 | — |
| Midwest Center for Clinical Research | Lee's Summit | Missouri | 64064 | — |
| Colon and Rectal Surgery, Inc | Omaha | Nebraska | 68114 | — |
| Impact Clinical Trials | Las Vegas | Nevada | 89106 | — |
| Gastroenterology Group & Endoscopy Center of South NJ (GGSJ) | Vineland | New Jersey | 08360-7072 | — |
| C&R Surgical Assoc of South Jersey | Voorhees Township | New Jersey | 08043-9544 | — |
| Life Medi-Research and Management | Brooklyn | New York | 11206 | — |
| HCCA Clinical Research Solutions | New York | New York | 10016 | — |
| Manhattan Surgical Associates, LLP | New York | New York | 10021 | — |
| Colorectal Associates of NY | New York | New York | 10022 | — |
| Medical Research Associates of New York (New York Gastroenterology Associates, LLP) | New York | New York | 10075 | — |
| Premier Medical Group | Poughkeepsie | New York | 12601 | — |
| Medispect | Boone | North Carolina | 28607 | — |
| Duke University | Durham | North Carolina | 27710 | — |
| Womack Army Medical Center | Fort Bragg | North Carolina | 28310-7301 | — |
| University of North Carolina | Raleigh | North Carolina | 27599 | — |
| Wake Research Associates | Raleigh | North Carolina | 27612 | — |
| Trial Management Associates | Wilmington | North Carolina | 28403 | — |
| University Hospitals Case Medical Center | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Dayton Gastroenterology, Inc. | Dayton | Ohio | 45415 | — |
| Great Lakes Gastroenterology | Mentor | Ohio | 44060 | — |
| Institute of Pain Research | Oklahoma City | Oklahoma | 73104 | — |
| Bend Memorial Clinic | Bend | Oregon | 97701 | — |
| The Corvallis Clinic, Clinical Research Center | Corvallis | Oregon | 97330 | — |
| Westover Heights Clinic | Portland | Oregon | 97210 | — |
| Penn State Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| West Penn Allegheny Health System | Monroeville | Pennsylvania | 15146 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19017 | — |
| Drexel Univ College of Medicine | Philadelphia | Pennsylvania | 19102 | — |
| Temple University Physicians, Jeanes Hospital | Philadelphia | Pennsylvania | 19111 | — |
| Pain Specialists of Charleston | North Charleston | South Carolina | 29406 | — |
| Gastroenterology Associates of Orangeburg, PA | Orangeburg | South Carolina | 29118 | — |
| HCCA Clinical Research Solutions | Jackson | Tennessee | 38305 | — |
| Vanderbilt Univ Dept of Colon and Rectal Surgery | Nashville | Tennessee | 37232 | — |
| Research Across America | Dallas | Texas | 75010 | — |
| Research Concepts, GP LLC | Houston | Texas | 77024 | — |
| University of TX Affiliated Hospitals | Houston | Texas | 77030 | — |
| Houston Endoscopy and Research Center | Houston | Texas | 77079 | — |
| Houston Digestive Disease Clinic | Houston | Texas | 77090-3408 | — |
| ColoProctology Associates | Seabrook | Texas | 77586 | — |
| University of Utah HSC | Salt Lake City | Utah | 84132 | — |
| Charlottesville Medical Research | Charlottesville | Virginia | 22911 | — |
| Gastroenterology Associates of Tidewater | Chesapeake | Virginia | 23320 | — |
| Jefferson Surgical Clinic | Roanoke | Virginia | 24016 | — |
| NW Gastroenterology | Bellevue | Washington | 98004 | — |
| Digestive Disease Institute, Virginia Mason Medical Center | Seattle | Washington | 98101 | — |
| Madigan Army Medical Center | Tacoma | Washington | 98431 | — |
| Medical College of Wisconsin Department of Surgery | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01690221, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 22, 2014 · Synced Apr 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01690221 live on ClinicalTrials.gov.