ClinicalTrials.gov record
Completed Phase 1 Interventional

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 in Adult Participants With Advanced or Refractory Solid Tumors or Lymphoma

ClinicalTrials.gov ID: NCT01703481

Public ClinicalTrials.gov record NCT01703481. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 11, 2026, 4:33 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493, a Pan-Fibroblast Growth Factor Receptor (FGFR) Tyrosine Kinase Inhibitor, in Subjects With Advanced or Refractory Solid Tumors or Lymphoma

Study identification

NCT ID
NCT01703481
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Janssen Research & Development, LLC
Industry
Enrollment
188 participants

Conditions and interventions

Interventions

  • JNJ-42756493: Part 1 Drug
  • JNJ-42756493: Part 2 Drug
  • JNJ-42756493: Part 3 Drug
  • JNJ-42756493: Part 4 Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 14, 2012
Primary completion
Jul 4, 2017
Completion
Jul 4, 2017
Last update posted
Feb 2, 2025

2012 – 2017

United States locations

U.S. sites
23
U.S. states
17
U.S. cities
23
Facility City State ZIP Site status
Not listed Birmingham Alabama
Not listed Tucson Arizona
Not listed La Jolla California
Not listed Los Angeles California
Not listed Sacramento California
Not listed Santa Monica California
Not listed Denver Colorado
Not listed Tampa Florida
Not listed Augusta Georgia
Not listed Chicago Illinois
Not listed Goshen Indiana
Not listed Boston Massachusetts
Not listed Detroit Michigan
Not listed St Louis Missouri
Not listed New Brunswick New Jersey
Not listed Albuquerque New Mexico
Not listed Charlotte North Carolina
Not listed Durham North Carolina
Not listed Nashville Tennessee
Not listed Dallas Texas
Not listed Houston Texas
Not listed Tyler Texas
Not listed Fairfax Virginia

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01703481, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 2, 2025 · Synced May 11, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01703481 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →