Akt Inhibitor MK2206, Lapatinib Ditosylate, and Trastuzumab in Treating Patients With Locally Advanced or Metastatic HER2-Positive Breast , Gastric, or Gastroesophageal Cancer That Cannot Be Removed By Surgery
Public ClinicalTrials.gov record NCT01705340. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase I Study of MK-2206 in Combination With Trastuzumab and Lapatinib in HER2-Positive Breast and Gastric Cancer
Study identification
- NCT ID
- NCT01705340
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- National Cancer Institute (NCI)
- NIH
- Enrollment
- 60 participants
Conditions and interventions
Conditions
- Adenocarcinoma of the Gastroesophageal Junction
- HER2-positive Breast Cancer
- Male Breast Cancer
- Recurrent Breast Cancer
- Recurrent Esophageal Cancer
- Recurrent Gastric Cancer
- Stage IIIC Breast Cancer
- Stage IIIC Esophageal Cancer
- Stage IIIC Gastric Cancer
- Stage IV Breast Cancer
- Stage IV Esophageal Cancer
- Stage IV Gastric Cancer
Interventions
- Akt inhibitor MK2206 Drug
- laboratory biomarker analysis Other
- lapatinib ditosylate Drug
- trastuzumab Biological
Drug · Other · Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 31, 2012
- Primary completion
- Apr 30, 2013
- Completion
- Not listed
- Last update posted
- Sep 29, 2013
Started 2012
United States locations
- U.S. sites
- 1
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10065 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01705340, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 29, 2013 · Synced May 19, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01705340 live on ClinicalTrials.gov.