Study of Safety, Tolerability & Efficacy of CK-2017357 in Amyotrophic Lateral Sclerosis (ALS)
Public ClinicalTrials.gov record NCT01709149. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase IIb, Multi-National, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Safety, Tolerability and Efficacy of CK-2017357 in Patients With Amyotrophic Lateral Sclerosis (ALS) (BENEFIT-ALS)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this research study is to evaluate the safety and effectiveness of CK-2017357 when taken with or without riluzole (also called Rilutek®) in patients with Amyotrophic Lateral Sclerosis (ALS).
Study identification
- NCT ID
- NCT01709149
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 711 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2012 (Type not available)
- Primary completion
- Mar 2014 (Actual)
- Completion
- Mar 2014 (Actual)
- Last update posted
- Mar 31, 2020
2012 – 2014
United States locations
- U.S. sites
- 44
- U.S. states
- 26
- U.S. cities
- 41
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Barrow Neurology | Phoenix | Arizona | 85013 | — |
| University of California, San Diego | La Jolla | California | 92093 | — |
| UC Irvine ALS & Neuromuscular Center | Orange | California | 92868 | — |
| Coordinated Clinical Research | San Diego | California | 92103 | — |
| California Pacific Medical Center Forbes Norris MDA/ALS Research Center | San Francisco | California | 94115 | — |
| Hospital for Special Care | New Britain | Connecticut | 06053 | — |
| The George Washington University | Washington D.C. | District of Columbia | 20037 | — |
| Mayo Clinic Florida Department of Neurology | Jacksonville | Florida | 32224 | — |
| Emory University, School of Medicine | Atlanta | Georgia | 30322 | — |
| Georgia Health Sciences University | Augusta | Georgia | 30912 | — |
| Indiana University Department of Neurology | Indianapolis | Indiana | 46202 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| University of Kansas | Kansas City | Kansas | 66160 | — |
| Johns Hopkins University | Baltimore | Maryland | 21205 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| University of Massachusetts Medical School | Worcester | Massachusetts | 01655 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| St Mary's Healthcare | Grand Rapids | Michigan | 49503 | — |
| Hennepin County Medical Center - Berman Center for Research | Minneapolis | Minnesota | 55415 | — |
| Saint Louis University | St Louis | Missouri | 63104 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| Neurology Associates | Lincoln | Nebraska | 68506 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Hospital for Special Surgery | New York | New York | 10021 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13120 | — |
| Carolinas Medical Center Department of Neurology | Charlotte | North Carolina | 27406 | — |
| Duke University | Durham | North Carolina | 27705 | — |
| Wake Forest University, School of Medicine | Winston-Salem | North Carolina | 27157 | — |
| Ohio State University Department of Neurology | Columbus | Ohio | 43221 | — |
| Providence ALS Center | Portland | Oregon | 97213 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| Penn State Hershey Neuroscience Clinics | Hershey | Pennsylvania | 17033 | — |
| Drexel Neurology | Philadelphia | Pennsylvania | 19107 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19107 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Texas Neurology | Dallas | Texas | 75214 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| UTHSCSA Department of Neurology | San Antonio | Texas | 78229 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
| West Virginia University Department of Neurology | Morgantown | West Virginia | 26506 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 31 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01709149, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 31, 2020 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01709149 live on ClinicalTrials.gov.