FOLFOX6m Plus SIR-Spheres Microspheres vs FOLFOX6m Alone in Patients With Liver Mets From Primary Colorectal Cancer
Public ClinicalTrials.gov record NCT01721954. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Assessment of Overall Survival of FOLFOX6m Plus SIR-Spheres Microspheres Versus FOLFOX6m Alone as First-line Treatment in Patients With Non-resectable Liver Metastases From Primary Colorectal Carcinoma in a Randomised Clinical Study
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is a randomized, multi-center study that will compare the efficacy and safety of selective internal radiation therapy (SIRT) using SIR-Spheres microspheres plus a standard chemotherapy regimen of FOLFOX6m versus FOLFOX6m alone as first-line therapy in patients with non-resectable liver metastases from primary colorectal carcinoma. Treatment with the biologic agent bevacizumab, if part of the standard of care at participating institutions, is allowed within this study at the discretion of the Investigator.
Study identification
- NCT ID
- NCT01721954
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 209 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 1, 2013 (Actual)
- Primary completion
- Dec 23, 2016 (Actual)
- Completion
- Feb 28, 2017 (Actual)
- Last update posted
- Nov 5, 2019
2013 – 2017
United States locations
- U.S. sites
- 18
- U.S. states
- 14
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| City of Hope | Duarte | California | 91010 | — |
| Orlando Health | Orlando | Florida | 32806 | — |
| Memorial Healthcare | Pembroke Pines | Florida | 33028 | — |
| University of Illinois Chicago | Chicago | Illinois | 60607 | — |
| Adventist Midwest Health | Hinsdale | Illinois | 60521 | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Roswell Park Cancer Center | Buffalo | New York | 14263 | — |
| Lenox Hill Hospital | New York | New York | 10075 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| Carolinas Medical Center | Charlotte | North Carolina | 28203 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Spartanburg Regional Healthcare / Gibbs Cancer Center | Spartanburg | South Carolina | 29303 | — |
| Methodist Hospital Dallas | Dallas | Texas | 75203 | — |
| St. Mark's Hospital | Salt Lake City | Utah | 84124 | — |
| Fletcher Allen Health Care | Burlington | Vermont | 05405 | — |
| West Virginia University Healthcare | Morgantown | West Virginia | 26506 | — |
| Aurora St. Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 65 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01721954, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 5, 2019 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01721954 live on ClinicalTrials.gov.