ClinicalTrials.gov record
Completed Phase 3 Interventional Results available

Study of Alirocumab (REGN727/SAR236553) added-on to Rosuvastatin Versus Other Lipid Modifying Treatments (LMT) (ODYSSEY OPTIONS II)

ClinicalTrials.gov ID: NCT01730053

Public ClinicalTrials.gov record NCT01730053. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 20, 2026, 9:41 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind Study of the Efficacy and Safety of REGN727 Added-on to Rosuvastatin Versus Ezetimibe Added-on to Rosuvastatin Versus Rosuvastatin Dose Increase in Patients Who Are Not Controlled on Rosuvastatin

Study identification

NCT ID
NCT01730053
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Regeneron Pharmaceuticals
Industry
Enrollment
305 participants

Conditions and interventions

Interventions

  • Alirocumab Drug
  • Ezetimibe Drug
  • Placebo Drug
  • Rosuvastatin Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 29, 2012
Primary completion
Apr 29, 2014
Completion
May 30, 2014
Last update posted
Apr 6, 2020

2012 – 2014

United States locations

U.S. sites
54
U.S. states
23
U.S. cities
54
Facility City State ZIP Site status
Not listed Chandler Arizona
Not listed Tucson Arizona
Not listed Anaheim California
Not listed Beverly Hills California
Not listed Fair Oaks California
Not listed Newport Beach California
Not listed Northridge California
Not listed Sacramento California
Not listed Walnut Creek California
Not listed Milford Connecticut
Not listed Atlantis Florida
Not listed Bradenton Florida
Not listed Clearwater Florida
Not listed Fort Lauderdale Florida
Not listed Jacksonville Florida
Not listed Lakeland Florida
(2 Locations) Miami Florida
Not listed Oviedo Florida
Not listed Pinellas Park Florida
Not listed Port Orange Florida
Not listed Sarasota Florida
Not listed Tampa Florida
Not listed West Palm Beach Florida
Not listed Winter Park Florida
Not listed Boise Idaho
Not listed Morton Illinois
Not listed Evansville Indiana
Not listed Indianapolis Indiana
Not listed Newton Kansas
Not listed Overland Park Kansas
Not listed Wichita Kansas
Not listed Lexington Kentucky
Not listed Louisville Kentucky
Not listed Auburn Maine
Not listed Bethesda Maryland
Not listed Edina Minnesota
Not listed Rochester Minnesota
Not listed Olive Branch Mississippi
Not listed Port Gibson Mississippi
Not listed St Louis Missouri
Not listed Butte Montana
Not listed Williamsville New York
Not listed Cincinnati Ohio
Not listed Marion Ohio
Not listed Portland Oregon
Not listed Warwick Rhode Island
Not listed Greer South Carolina
Not listed Summerville South Carolina
Not listed Kingsport Tennessee
Not listed Dallas Texas
Not listed Fort Worth Texas
Not listed Houston Texas
Not listed Bountiful Utah
Not listed Salt Lake City Utah

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 39 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01730053, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 6, 2020 · Synced May 20, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01730053 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →