Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease
Public ClinicalTrials.gov record NCT01776424. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Controlled Trial of Rivaroxaban for the Prevention of Major Cardiovascular Events in Patients With Coronary or Peripheral Artery Disease (COMPASS - Cardiovascular OutcoMes for People Using Anticoagulation StrategieS).
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objectives of this study are: * To determine whether rivaroxaban 2.5 mg twice daily (bid) + aspirin 100 mg once daily (od) compared with aspirin 100 mg od reduces the risk of a composite of myocardial infarction, stroke, or cardiovascular death in subjects with coronary artery disease (CAD) or peripheral artery disease (PAD); * To determine whether rivaroxaban 5 mg bid compared with aspirin 100 mg od reduces the risk of a composite of myocardial infarction, stroke or cardiovascular death in subjects with CAD or PAD.
Study identification
- NCT ID
- NCT01776424
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 27,395 participants
Conditions and interventions
Conditions
Interventions
- Rivaroxaban (Xarelto, BAY59-7939) Drug
- Aspirin Drug
- Aspirin placebo Drug
- Rivaroxaban placebo Drug
- Pantoprazole Drug
- Pantoprazole placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 28, 2013 (Actual)
- Primary completion
- Jul 21, 2017 (Actual)
- Completion
- Jun 15, 2021 (Actual)
- Last update posted
- Nov 28, 2022
2013 – 2021
United States locations
- U.S. sites
- 53
- U.S. states
- 21
- U.S. cities
- 52
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | 35294 | — |
| Not listed | Mobile | Alabama | 36608 | — |
| Not listed | Anaheim | California | 92801 | — |
| Not listed | Laguna Hills | California | 92653 | — |
| Not listed | Northridge | California | 91324 | — |
| Not listed | Palo Alto | California | 94304-1207 | — |
| Not listed | Santa Rosa | California | 95494 | — |
| Not listed | Sylmar | California | 91342 | — |
| Not listed | Torrance | California | 90502-2004 | — |
| Not listed | Norwalk | Connecticut | 06851 | — |
| Not listed | Stamford | Connecticut | 06905 | — |
| Not listed | Trumbull | Connecticut | 06611 | — |
| Not listed | Atlantis | Florida | 33462 | — |
| Not listed | Clearwater | Florida | 33756 | — |
| Not listed | Coral Springs | Florida | 33065 | — |
| Not listed | Jacksonville Beach | Florida | 32250 | — |
| Not listed | Largo | Florida | 33770 | — |
| Not listed | New Port Richey | Florida | 34653 | — |
| Not listed | Safety Harbor | Florida | 34695 | — |
| Not listed | Sarasota | Florida | 34239 | — |
| Not listed | Meridian | Idaho | 83716 | — |
| Not listed | Arlington Heights | Illinois | 60005 | — |
| Not listed | Hazel Crest | Illinois | 60429 | — |
| Not listed | Davenport | Iowa | 52803 | — |
| Not listed | West Des Moines | Iowa | 50266 | — |
| Not listed | Crestview Hills | Kentucky | 41017-5460 | — |
| Not listed | Baltimore | Maryland | 21215 | — |
| Not listed | Haverhill | Massachusetts | 01830 | — |
| Not listed | Alpena | Michigan | 49707 | — |
| Not listed | Jackson | Michigan | 49201 | — |
| Not listed | St Louis | Missouri | 63136 | — |
| Not listed | Kalispell | Montana | 59901 | — |
| Not listed | New Brunswick | New Jersey | 08901 | — |
| Not listed | Cortlandt Manor | New York | 10567 | — |
| Not listed | Kingston | New York | 12401 | — |
| Not listed | Saratoga Springs | New York | 12866 | — |
| Not listed | Durham | North Carolina | 27713 | — |
| Not listed | Pinehurst | North Carolina | 28374 | — |
| Not listed | Elyria | Ohio | 44035 | — |
| Not listed | Sandusky | Ohio | 44870 | — |
| Not listed | Toledo | Ohio | 43606 | — |
| Not listed | Doylestown | Pennsylvania | 18901 | — |
| Not listed | Langhorne | Pennsylvania | 19047 | — |
| Not listed | Yardley | Pennsylvania | 19067 | — |
| Not listed | Sioux Falls | South Dakota | 57108 | — |
| Not listed | Dallas | Texas | 75216-7167 | — |
| Not listed | Houston | Texas | 77030-4298 | — |
| Not listed | Houston | Texas | 77030 | — |
| Not listed | San Antonio | Texas | 78229 | — |
| Not listed | Bellevue | Washington | 98004-4623 | — |
| Not listed | Puyallup | Washington | 98372 | — |
| Not listed | Seattle | Washington | 98195 | — |
| Not listed | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 512 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01776424, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 28, 2022 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01776424 live on ClinicalTrials.gov.