ClinicalTrials.gov record
Active, not recruiting Phase 1 Interventional

BYL719 and Letrozole in Post-Menopausal Patients With Hormone Receptor-Positive Metastatic Breast Cancer

ClinicalTrials.gov ID: NCT01791478

Public ClinicalTrials.gov record NCT01791478. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 18, 2026, 4:03 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase Ib Trial of BYL719 (an α-Specific PI3K Inhibitor) in Combination With Endocrine Therapy in Post-Menopausal Patients With Hormone Receptor-Positive Metastatic Breast Cancer

Study identification

NCT ID
NCT01791478
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Enrollment
46 participants

Conditions and interventions

Interventions

  • PI3K inhibitor BYL719 Drug
  • laboratory biomarker analysis Other
  • letrozole Drug
  • pharmacological studies Other

Drug · Other

Eligibility (public fields only)

Age range
18 Years and older
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2013
Primary completion
Nov 30, 2014
Completion
Feb 27, 2025
Last update posted
Jul 22, 2024

2013 – 2025

United States locations

U.S. sites
2
U.S. states
2
U.S. cities
2
Facility City State ZIP Site status
Massachusetts General Hospital, Dana-Farber Cancer Institute Boston Massachusetts 02114
Vanderbilt-Ingram Cancer Center Nashville Tennessee 37232-6838

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01791478, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 22, 2024 · Synced May 18, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01791478 live on ClinicalTrials.gov.

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