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Completed Phase 2 Interventional Results available

Dovitinib for Patients With Tumor Pathway Activations Inhibited by Dovitinib

ClinicalTrials.gov ID: NCT01831726

Public ClinicalTrials.gov record NCT01831726. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 1:32 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Modular Phase II Study to Link Targeted Therapy to Patients With Pathway Activated Tumors: Module 2 - Dovitinib for Patients With Tumor Pathway Activations Inhibited by Dovitinib Including Tumors With Mutations or Translocations of FGFR, PDGFR, VEGF, cKIT, FLT3, CSFR1, Trk and RET

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this signal seeking study was to determine whether treatment with dovitinib (TKI258) demonstrated sufficient efficacy in select pathway-activated solid tumors and/or hematologic malignancies to warrant further study.

Study identification

NCT ID
NCT01831726
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
80 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 100 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 2013 (Type not available)
Primary completion
Dec 2015 (Actual)
Completion
Dec 2015 (Actual)
Last update posted
Mar 20, 2017

2013 – 2015

United States locations

U.S. sites
49
U.S. states
27
U.S. cities
46
Facility City State ZIP Site status
Alabama Oncology Birmingham Alabama 35211 —
Highlands Oncology Group SC Fayetteville Arkansas 72703 —
PCR Oncology Pismo Beach California 93449 —
Sarcoma Oncology Center Santa Monica California 90403 —
Rocky Mountain Cancer Centers Rocky Mountain Cancer Centers Greenwood Village Colorado — —
Whittingham Cancer Center Norwalk Hospital Norwalk Connecticut 06856 —
Memorial Cancer Institute Memorial Healthcare System Hollywod Florida 33021 —
Cancer Specialists of North Florida Cancer Specialists (2) Jacksonville Florida 32256 —
Florida Hospital Cancer Institute Orlando Florida 32804 —
Space Coast Medical Associates Space Coast Cancer Center Titusville Florida 32796 —
University Cancer & Blood Center, LLC Athens Georgia 30607 —
NorthWest Georgia Oncology Centers NW Georgia Oncology Marietta Georgia 30060 —
Lurie Children's Hospital of Chicago Developmental Therapeutics Chicago Illinois 60611 —
Illinois Cancer Care Peoria Illinois 61615-7828 —
Indiana University Indiana Univ. - Purdue Univ. Indianapolis Indiana 46202 —
Horizon Oncology Center Horizon Oncology Ctr. Lafayette Indiana 47905 —
St. Agnes Hospital St. Agnes Hospital (2) Baltimore Maryland 21229 —
University of Michigan Int. Medicine Oncology Ann Arbor Michigan 48109 —
Minnesota Oncology Hematology, P.A. Minnesota Oncology Hematology Minneapolis Minnesota 55404 —
Billings Clinic Onc Dept Billings Montana 59107 —
Southeast Nebraska Oncology Cancer Center Lincoln Nebraska 68510 —
Comprehensive Cancer Centers of Nevada CCC of Nevada- Southwest (2) Las Vegas Nevada 89109 —
Waverly Hematology Oncology Cary North Carolina 27518 —
Oncology Hematology Care, Inc. Oncology Hematology Care (2) Cincinnati Ohio 45242 —
Cleveland Clinic Foundation Cleveland Clinic (19) Cleveland Ohio 44195 —
St. Charles Cancer Center Bend Oregon 97701 —
Oregon Health & Science University OHSU Knight Cancer Institute Portland Oregon 97239 —
University of Pittsburgh Cancer Institute Pittsburgh Pennsylvania 15232-1305 —
Rhode Island Hospital Rhode Island Hosp. (2) Providence Rhode Island 02903 —
Gibbs Cancer Center & Research Institute Spartanburg Reg. Healthcare Spartanburg South Carolina 29303 —
Chattanooga Oncology and Hematology Assoicates, PC Chattanooga Oncology Chattanooga Tennessee 37404 —
The West Clinic Memphis Tennessee 38120 —
Sarah Cannon Research Institute Tennessee Oncology Nashville Tennessee 37203 —
Austin Cancer Centers Austin Cancer Center (2) Austin Texas 78759 —
Texas Oncology Texas Oncology - Sammons Dallas Texas 75246 —
Texas Oncology Midtown Texas Oncology Dallas Texas 75251 —
The Center for Cancer and Blood Disorders Fort Worth Texas 76104 —
Oncology Consultants Oncology Group Houston Texas 77024 —
MD Anderson Cancer Center/University of Texas MD Anderson Cancer Center (3) Houston Texas 77030 —
Tyler Cancer Center Tyler Texas 75702 —
Intermountain Medical Center Intermountain Healthcare Murray Utah 84157 —
Virginia Cancer Specialists Virginia Cancer Specialists Fairfax Virginia 22031 —
Providence Regional Cancer Partnership Providence Reg. Cancer (2) Everett Washington 98201 —
Evergreen Hematology & Oncology Spokane Washington 99218 —
Northwest Medical Specialties Hematology/Oncology Tacoma Washington 98405 —
Wenatchee Valley Medical Center Wenatchee Valley Wenatchee Washington 98801 —
Yakima Valley Memorial Hospital North Star Lodge Cancer Center Yakima Washington 98902 —
Aurora Research Institute Milwaukee Wisconsin 53226 —
Medical College of Wisconsin Cancer Ctr.-Froedtert Hospital Milwaukee Wisconsin 53226 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01831726, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 20, 2017 · Synced Oct 21, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01831726 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →