Phase 3 Study Evaluating Efficacy and Safety of DSC127 Compared With Vehicle and With Standard-of-care in Diabetic Foot Ulcers
Public ClinicalTrials.gov record NCT01849965. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Parallel-group, Vehicle and Standard of Care-controlled Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of DSC127 in Treating Non-healing Foot Ulcers in Subjects With Diabetes Mellitus
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To determine if aclerastide (DSC127) is effective in increasing incidence of complete wound closure up to 10 weeks confirmed 2 weeks later, compared with vehicle (gel without active ingredient) and compared with a standard-of-care gel, in subjects with diabetes mellitus (DM) who have chronic Wagner Grade 1 or 2 diabetic foot ulcers, 0.75 - 6cm2 in size.
Study identification
- NCT ID
- NCT01849965
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 396 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2013 (Type not available)
- Primary completion
- Dec 2015 (Actual)
- Completion
- Dec 2015 (Actual)
- Last update posted
- Dec 12, 2017
2013 – 2015
United States locations
- U.S. sites
- 33
- U.S. states
- 13
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| East Valley Foot and Ankle Specialist | Mesa | Arizona | 85206 | — |
| Arizona Burn Center Maricopa Medical Center | Phoenix | Arizona | 85008 | — |
| Associated Foot & Ankle Specialists, PC | Phoenix | Arizona | 85015 | — |
| Ledesma Foot and Ankle | Phoenix | Arizona | 85032 | — |
| Precision Trials | Phoenix | Arizona | 85032 | — |
| Center for Clinical Research, Inc. | Castro Valley | California | 94546 | — |
| Reliance Institute of Clinical Research | Chino | California | 91710 | — |
| Vladimir Zeetser, DPM | Encino | California | 91316 | — |
| Innovative Medical Technologies, LLC | Los Angeles | California | 90063 | — |
| Samuel Merritt University, California School of Podiatric Medicine | Oakland | California | 94609 | — |
| Center for Clinical Research, Inc. | San Francisco | California | 94115 | — |
| The Diabetic Foot and Wound Center | Denver | Colorado | 80220 | — |
| Orthopedic Research Associates | Boynton Beach | Florida | 33472 | — |
| Invesclinic, LLC | Fort Lauderdale | Florida | 33308 | — |
| Research in Miami, Inc. | Hialeah | Florida | 33013 | — |
| River City Clinical Research | Jacksonville | Florida | 32207 | — |
| Advanced Pharma CR, LLC | Miami | Florida | 33136 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Phoenix Medical Research | Miami | Florida | 33165 | — |
| New Phase Clincal Trials, Inc. | Miami Beach | Florida | 33140 | — |
| Bluegrass Foot Center c/o Research Concierge, LLC | Owensboro | Kentucky | 42303 | — |
| Grace Research | Shreveport | Louisiana | 71101 | — |
| American Center for Clinical Trials | Southfield | Michigan | 48034 | — |
| Dr. Vincent Giacalone | Emerson | New Jersey | 07630 | — |
| Wayne Memorial Hospital | Goldsboro | North Carolina | 27533 | — |
| O'Malley Foot and Ankle | Wilmington | North Carolina | 24801 | — |
| Regional Infectious Disease & Infusion Center Inc. | Lima | Ohio | 45801 | — |
| Paddington Testing Clinic | Philadelphia | Pennsylvania | 19103 | — |
| Martin Foot & Ankle | York | Pennsylvania | 17403 | — |
| North Texas Podiatric Medicine & Surgery | Dallas | Texas | 75231 | — |
| Bone and Joint Institute | Fort Worth | Texas | 76104 | — |
| Houston Foot & Ankle Specialists | Houston | Texas | 77074 | — |
| Redwood Health Center | Salt Lake City | Utah | 84119 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 23 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01849965, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 12, 2017 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01849965 live on ClinicalTrials.gov.