A Randomized Phase 2 Study of Atezolizumab (an Engineered Anti-PDL1 Antibody) Compared With Docetaxel in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Failed Platinum Therapy - "POPLAR"
Public ClinicalTrials.gov record NCT01903993. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Open-label, Multicenter, Randomized Study to Investigate the Efficacy and Safety of MPDL3280A (Anti-PD-L1 Antibody) Compared With Docetaxel in Patients With Non-Small Cell Lung Cancer After Platinum Failure
Study identification
- NCT ID
- NCT01903993
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 287 participants
Conditions and interventions
Conditions
Interventions
- Atezolizumab Drug
- Docetaxel Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 5, 2013
- Primary completion
- Nov 18, 2015
- Completion
- Sep 5, 2018
- Last update posted
- Oct 1, 2019
2013 – 2018
United States locations
- U.S. sites
- 29
- U.S. states
- 19
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Oncology Associates, PC - HOPE | Tucson | Arizona | 85704 | — |
| Genesis Cancer Center | Hot Springs | Arkansas | 71913 | — |
| Loma Linda University Medical Center | Loma Linda | California | 92354 | — |
| Kaiser Permanente - San Marcos | San Marcos | California | 92069 | — |
| Kaiser Permanente - Vallejo | Vallejo | California | 94589 | — |
| Innovative Clinical Research Institute | Whittier | California | 90603 | — |
| Rocky Mountain Cancer Centers - Colorado Springs (Circle) | Lone Tree | Colorado | 80124 | — |
| Ocala Oncology Center | Ocala | Florida | 34471 | — |
| Georgia Cancer Specialists | Atlanta | Georgia | 30341 | — |
| Ingalls Memorial Hospital | Harvey | Illinois | 60426 | — |
| Illinois Cancer Care | Peoria | Illinois | 61615 | — |
| New England Cancer Specialists | Scarborough | Maine | 04074 | — |
| Karmanos Cancer Institute.. | Detroit | Michigan | 48201 | — |
| Billings Clinic; Research Center | Billings | Montana | 59101 | — |
| Comprehensive Cancer Centers of Nevada - Eastern Avenue | Las Vegas | Nevada | 89169 | — |
| The Valley Hospital | Paramus | New Jersey | 07652 | — |
| New York Oncology Hematology, P.C. | Albany | New York | 12206 | — |
| Broome Oncology - Binghamton | Binghamton | New York | 13905 | — |
| Willamette Valley Cancer Ctr - 520 Country Club | Eugene | Oregon | 97401-8122 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Center for Biomedical Research LLC | Knoxville | Tennessee | 37909 | — |
| Texas Oncology - South Austin | Austin | Texas | 78745 | — |
| Texas Oncology, P.A. - Fort Worth | Fort Worth | Texas | 76104 | — |
| Virginia Cancer Specialists, PC | Fairfax | Virginia | 22031 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
| Blue Ridge Cancer Care | Roanoke | Virginia | 24014 | — |
| Northwest Cancer Specialists - Vancouver | Vancouver | Washington | 98684 | — |
| Providence St. Mary Regional Cancer Center | Walla Walla | Washington | 99362 | — |
| Wenatchee Valley Hospital & Clinics | Wenatchee | Washington | 98801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 36 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01903993, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 1, 2019 · Synced May 3, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01903993 live on ClinicalTrials.gov.