Efficacy and Safety Study of MYOBLOC® in the Treatment of Sialorrhea in Adult Subjects

ClinicalTrials.gov ID: NCT01994109

Public ClinicalTrials.gov record NCT01994109. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Oct 22, 2026, 6:14 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 3, Multicenter, Double-Blind, Placebo-Controlled, Single-Treatment Efficacy and Safety Study of MYOBLOC® Followed by Open-Label, Multiple-Treatment With MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adult Subjects

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will evaluate the efficacy and safety of MYOBLOC in the treatment of Sialorrhea (drooling), which can be a symptom of many disease conditions. MYOBLOC will be injected directly into the salivary glands. MYOBLOC has been shown in previous trials to safely decrease saliva production, thereby demonstrating its potential as a safe and effective treatment for troublesome sialorrhea.

Study identification

NCT ID: NCT01994109
Recruitment status: Completed
Study type: Interventional
Phase: Phase 3
Lead sponsor: Solstice Neurosciences, LLC, a subsidiary of US WorldMeds, LLC; Industry
Enrollment: 187 participants

Conditions and interventions

Conditions

Sialorrhea

Interventions

MYOBLOC Drug
PLACEBO Other

Drug · Other

Eligibility (public fields only)

Age range: 18 Years to 85 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Nov 2013 (Type not available)
Primary completion: Jan 2016 (Actual)
Completion: Jan 2017 (Actual)
Last update posted: Apr 21, 2026

2013 – 2017

United States locations

U.S. sites: 24
U.S. states: 17
U.S. cities: 24

Facility	City	State	ZIP	Site status
Not listed	Loma Linda	California	92354	—
Not listed	Los Angeles	California	90033	—
Not listed	National City	California	91950	—
Not listed	Aurora	Colorado	80045	—
Not listed	Washington D.C.	District of Columbia	20007	—
Not listed	Boca Raton	Florida	33486	—
Not listed	Port Charlotte	Florida	33980	—
Not listed	Carmel	Indiana	46032	—
Not listed	Baltimore	Maryland	21287	—
Not listed	Elkridge	Maryland	21075	—
Not listed	Detroit	Michigan	48334	—
Not listed	St Louis	Missouri	63110	—
Not listed	Edison	New Jersey	08818	—
Not listed	Albany	New York	12208	—
Not listed	New York	New York	10003	—
Not listed	Cincinnati	Ohio	45219	—
Not listed	Tulsa	Oklahoma	74136	—
Not listed	Port Royal	South Carolina	29935	—
Not listed	Cordova	Tennessee	38018	—
Not listed	Houston	Texas	77030	—
Not listed	San Antonio	Texas	78229	—
Not listed	Salt Lake City	Utah	84132	—
Not listed	Kirkland	Washington	98034	—
Not listed	Tacoma	Washington	98409	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT01994109, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 21, 2026 · Synced Oct 22, 2026

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01994109 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →