Assessment of the Efficacy and Safety of Olaparib Monotherapy Versus Physicians Choice Chemotherapy in the Treatment of Metastatic Breast Cancer Patients With Germline BRCA1/2 Mutations.
Public ClinicalTrials.gov record NCT02000622. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Open Label, Randomised, Controlled, Multi-centre Study to Assess the Efficacy and Safety of Olaparib Monotherapy Versus Physicians Choice Chemotherapy in the Treatment of Metastatic Breast Cancer Patients With Germline BRCA1/2 Mutations.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This open label, randomised, controlled, multi-centre phase III study will assess the efficacy and safety of single agent olaparib vs standard of care based on physician's choice of capecitabine, vinorelbine or eribulin in metastatic breast cancer patients with gBRCA 1/2 mutations.
Study identification
- NCT ID
- NCT02000622
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 302 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 99 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 27, 2014 (Actual)
- Primary completion
- Dec 9, 2016 (Actual)
- Completion
- Dec 23, 2025 (Actual)
- Last update posted
- Feb 13, 2026
2014 – 2025
United States locations
- U.S. sites
- 42
- U.S. states
- 22
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | San Diego | California | 92123 | — |
| Research Site | Santa Rosa | California | 95403 | — |
| Research Site | Whittier | California | 90602 | — |
| Research Site | Denver | Colorado | 80204 | — |
| Research Site | New Haven | Connecticut | 06510 | — |
| Research Site | Washington D.C. | District of Columbia | 20007 | — |
| Research Site | Jacksonville | Florida | 32224 | — |
| Research Site | Orlando | Florida | 32804 | — |
| Research Site | Plantation | Florida | 33324 | — |
| Research Site | Columbus | Georgia | 31904 | — |
| Research Site | Marietta | Georgia | 30060 | — |
| Research Site | Chicago | Illinois | 60612 | — |
| Research Site | Niles | Illinois | 60714 | — |
| Research Site | Wichita | Kansas | 67214 | — |
| Research Site | Lafayette | Louisiana | 70506 | — |
| Research Site | Boston | Massachusetts | 02114 | — |
| Research Site | Boston | Massachusetts | 02118 | — |
| Research Site | Boston | Massachusetts | 02215 | — |
| Research Site | Detroit | Michigan | 48201 | — |
| Research Site | Grand Rapids | Michigan | 49503 | — |
| Research Site | Rochester | Minnesota | 55905-0001 | — |
| Research Site | Saint Louis Park | Minnesota | 55416 | — |
| Research Site | Jackson | Mississippi | 39202 | — |
| Research Site | Columbia | Missouri | 65212 | — |
| Research Site | St Louis | Missouri | 63131 | — |
| Research Site | Lebanon | New Hampshire | 03756 | — |
| Research Site | Commack | New York | 11725 | — |
| Research Site | Harrison | New York | 10604 | — |
| Research Site | New York | New York | 10021 | — |
| Research Site | New York | New York | 10065 | — |
| Research Site | Rockville Centre | New York | 11570 | — |
| Research Site | Syracuse | New York | 13210 | — |
| Research Site | Cincinnati | Ohio | 45267 | — |
| Research Site | Cleveland | Ohio | 44106 | — |
| Research Site | Cleveland | Ohio | 44195 | — |
| Research Site | Portland | Oregon | 97213 | — |
| Research Site | Philadelphia | Pennsylvania | 19104 | — |
| Research Site | Sayre | Pennsylvania | 18840 | — |
| Research Site | Germantown | Tennessee | 38138 | — |
| Research Site | Houston | Texas | 77030 | — |
| Research Site | Tyler | Texas | 75701 | — |
| Research Site | Burlington | Vermont | 05401 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 129 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02000622, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 13, 2026 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02000622 live on ClinicalTrials.gov.