LDE225 for Patients With PTCH1 or SMO Mutated Tumors
Public ClinicalTrials.gov record NCT02002689. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Modular Phase II Study to Link Targeted Therapy to Patients With Pathway Activated Tumors: Module - 5 LDE225 for Patients With PTCH1 or SMO Mutated Tumors
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this signal seeking study is to determine whether treatment with LDE225 demonstrates sufficient efficacy in hedgehog pathway-mutated solid tumors and/or hematologic malignancies to warrant further study
Study identification
- NCT ID
- NCT02002689
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 10 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 2014 (Type not available)
- Primary completion
- Mar 2015 (Actual)
- Completion
- Mar 2015 (Actual)
- Last update posted
- May 2, 2016
2014 – 2015
United States locations
- U.S. sites
- 10
- U.S. states
- 9
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of California Davis Cancer Center UC Davis Cancer (3) | Sacramento | California | 95817 | — |
| Rocky Mountain Cancer Centers RMCC - Aurora | Greenwood Village | Colorado | — | — |
| Lurie Children's Hospital of Chicago Developmental Therapeutics | Chicago | Illinois | 60611 | — |
| Minnesota Oncology Hematology, P.A. Southdate Medical Center | Minneapolis | Minnesota | 55404 | — |
| Cleveland Clinic Foundation Cleveland Clinic (19) | Cleveland | Ohio | 44195 | — |
| Sanford Research Sanford Health | Sioux Falls | South Dakota | 57104 | — |
| Oncology Consultants Oncology Group | Houston | Texas | 77024 | — |
| MD Anderson Cancer Center/University of Texas MD Anderson Cancer Center (3) | Houston | Texas | 77030 | — |
| Intermountain Medical Center Intermountain Healthcare | Murray | Utah | 84157 | — |
| Seattle Cancer Care Alliance Skagit Valley Hospital | Seattle | Washington | 98109-1023 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02002689, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 2, 2016 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02002689 live on ClinicalTrials.gov.