Efficacy and Safety of Allogeneic Mesenchymal Precursor Cells (Rexlemestrocel-L) for the Treatment of Heart Failure
Public ClinicalTrials.gov record NCT02032004. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Double-blind, Randomized, Sham-procedure-controlled, Parallel-Group Efficacy and Safety Study of Allogeneic Mesenchymal Precursor Cells (Rexlemestrocel-L) in Chronic Heart Failure Due to LV Systolic Dysfunction (Ischemic or Nonischemic) Dream HF-1
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to determine whether transendocardial delivery of allogeneic human bone marrow-derived mesenchymal precursor cells (MPCs \[rexlemestrocel-L\]) is effective in the treatment of chronic heart failure (HF) due to left ventricular (LV) systolic dysfunction.
Study identification
- NCT ID
- NCT02032004
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 565 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 3, 2014 (Actual)
- Primary completion
- Jan 30, 2020 (Actual)
- Completion
- Jan 30, 2020 (Actual)
- Last update posted
- Mar 23, 2026
2014 – 2020
United States locations
- U.S. sites
- 56
- U.S. states
- 23
- U.S. cities
- 48
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mesoblast Investigational Site 10757 - Cardiology, P.C. | Birmingham | Alabama | 35211 | — |
| Mesoblast Investigational Site 13262 - University of Alabama at Birmingham Hospital | Birmingham | Alabama | 35233 | — |
| Mesoblast Investigational Site 10779 - Mercy Gilbert Medical Center | Gilbert | Arizona | 85297 | — |
| Mesoblast Investigational Site 10786 - Cardiovascular Associates of Mesa | Mesa | Arizona | 85206 | — |
| Mesoblast Investigational Site 10756 - Mayo Clinic | Phoenix | Arizona | 85054 | — |
| Mesoblast Investigational Site 13023 - University of Arizona Medical Center | Tucson | Arizona | 85724 | — |
| Mesoblast Investigational Site 10754 - University of California, San Diego | La Jolla | California | 92037 | — |
| Mesoblast Investigational Site 10759 - Scripps Clinic | La Jolla | California | 92037 | — |
| Mesoblast Investigational Site 13265 - University of California, Los Angeles | Los Angeles | California | 90045 | — |
| Mesoblast Investigational Site 10775 - Cedars-Sinai Medical Care Foundation | Los Angeles | California | 90211 | — |
| Mesoblast Investigational Site 10778 - Orange County Cardiology | Orange | California | 92868 | — |
| Mesoblast Investigational Site 13031 - St. John's Regional Medical Center | Oxnard | California | 93030 | — |
| Mesoblast Investigational Site 13275 - Stanford University Hospital | Stanford | California | 94305 | — |
| Mesoblast Investigational Site 13267 - Bethesda Heart Hospital | Boynton Beach | Florida | 33435 | — |
| Mesoblast Investigational Site 10780 - Morton Plant Hospital | Clearwater | Florida | 33756 | — |
| Mesoblast Investigational Site 10760 - Shands Hospital, University of Florida | Gainesville | Florida | 32610 | — |
| Mesoblast Investigational Site 13273 - University of Florida Health | Jacksonville | Florida | 32209 | — |
| Mesoblast Investigational Site 10768 - University of Miami | Miami | Florida | 33215 | — |
| Mesoblast Investigational Site 13280 | Orlando | Florida | — | — |
| Mesoblast Investigational Site 13264 - Florida Hospital Pepin Heart Institute | Tampa | Florida | 33613 | — |
| Mesoblast Investigational Site 13027 - Emory University School of Medicine | Atlanta | Georgia | 30322 | — |
| Mesoblast Investigational Site 10765 - Georgia Regents University | Augusta | Georgia | 30912 | — |
| Mesoblast Investigational Site 10772 - University Cardiologist, Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Mesoblast Investigational Site 13030 - University of Iowa | Iowa City | Iowa | 52242 | — |
| Mesoblast Investigational Site 10783 - Gill Heart Institute, University of Kentucky | Lexington | Kentucky | 40536 | — |
| Mesoblast Investigational Site 13022 - University of Louisville | Louisville | Kentucky | 40202 | — |
| Mesoblast Investigational Site 13266 | New Orleans | Louisiana | — | — |
| Mesoblast Investigational Site 10782 | Boston | Massachusetts | — | — |
| Mesoblast Investigational Site 10766 - Michigan Cardiovascular Institute | Saginaw | Michigan | 48602 | — |
| Mesoblast Investigational Site 10762 - Minneapolis Heart Institute | Minneapolis | Minnesota | 55407 | — |
| Mesoblast Investigational Site 10761 - Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Mesoblast Investigational Site 13281 | Las Vegas | Nevada | — | — |
| Mesoblast Investigational Site 13263 - RWJ Barnabas Heart Center | Newark | New Jersey | 07112 | — |
| Mesoblast Investigational Site 10776 - Columbia University Medical Center | New York | New York | 10032 | — |
| Mesoblast Investigational Site 13026 - Sanger Heart and Vascular Institute, Carolinas Healthcare System | Charlotte | North Carolina | 28203 | — |
| Mesoblast Investigational Site 10781 - Duke University | Durham | North Carolina | 27710 | — |
| Mesoblast Investigational Site 10758 - The Christ Hospital | Cincinnati | Ohio | 45219 | — |
| Mesoblast Investigational Site 10770 - University of Cincinnati | Cincinnati | Ohio | 45267 | — |
| Mesoblast Investigational Site 10773 | Cleveland | Ohio | — | — |
| Mesoblast Investigational Site 13278 - OhioHealth Research Institute | Columbus | Ohio | 43214 | — |
| Mesoblast Investigational Site 10785 - Lehigh Valley Hospital | Allentown | Pennsylvania | 18103 | — |
| Mesoblast Investigational Site 13261 - University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Mesoblast Investigational Site 10767 - Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| Mesoblast Investigational Site 13277 | Philadelphia | Pennsylvania | — | — |
| Mesoblast Investigational Site 10774 - University of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Mesoblast Investigational Site 10777 - Stern Cardiovascular Foundation | Germantown | Tennessee | 38125 | — |
| Mesoblast Investigational Site 13024 - Austin Heart, PLLC | Austin | Texas | 78756 | — |
| Mesoblast Investigational Site 13274 - Soltero CV Research Center, Baylor Scott & White Research Institute | Dallas | Texas | 75226 | — |
| Mesoblast Investigational Site 10755 - Texas Heart Institute | Houston | Texas | 77030 | — |
| Mesoblast Investigational Site 13268 - Houston Methodist Hospital | Houston | Texas | 77030 | — |
| Mesoblast Investigational Site 10763 - University Hospital | Salt Lake City | Utah | 84132 | — |
| Mesoblast Investigational Site 10771 - Heart & Vascular Research, Swedish Medical Center | Seattle | Washington | 98122 | — |
| Mesoblast Investigational Site 10764 - University of Wisconsin | Madison | Wisconsin | 53792 | — |
| Mesoblast Investigational Site 10769 - Aurora Healthcare | Milwaukee | Wisconsin | 53215 | — |
| Mesoblast Investigational Site 13279 | Milwaukee | Wisconsin | — | — |
| Mesoblast Investigational Site 10789 - Aspirus Research Institute | Wausau | Wisconsin | 54401 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02032004, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 23, 2026 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02032004 live on ClinicalTrials.gov.