ClinicalTrials.gov record

Active, not recruiting Phase 2 Interventional Accepts healthy volunteers Results available

Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure

ClinicalTrials.gov ID: NCT02105766

Public ClinicalTrials.gov record NCT02105766. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Apr 29, 2026, 8:28 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia in Individuals With Higher Risk of Transplant Failure

Study identification

NCT ID: NCT02105766
Recruitment status: Active, not recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Enrollment: 56 participants

Conditions and interventions

Conditions

Interventions

Alemtuzumab Drug
Cyclophosphamide Drug
Filgrastim Drug
Pentostatin Drug
Radiotherapy Procedure
Sirolimus Drug

Drug · Procedure

Eligibility (public fields only)

Age range: 4 Years to 80 Years
Sex: All
Healthy volunteers: Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Apr 20, 2014
Primary completion: Dec 30, 2023
Completion: Dec 30, 2027
Last update posted: Mar 10, 2025

2014 – 2027

United States locations

U.S. sites: 1
U.S. states: 1
U.S. cities: 1

Facility	City	State	ZIP	Site status
National Institutes of Health Clinical Center	Bethesda	Maryland	20892	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT02105766, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Mar 10, 2025 · Synced Apr 29, 2026

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The complete protocol, eligibility criteria, and contact information for NCT02105766 live on ClinicalTrials.gov.

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