A Study of Abemaciclib (LY2835219) in Participants With Previously Treated KRAS Mutated Lung Cancer
Public ClinicalTrials.gov record NCT02152631. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
JUNIPER: A Randomized Phase 3 Study of Abemaciclib Plus Best Supportive Care Versus Erlotinib Plus Best Supportive Care in Patients With Stage IV NSCLC With a Detectable KRAS Mutation Who Have Progressed After Platinum-Based Chemotherapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study is to evaluate how safe and effective the study drug known as abemaciclib is in participants with lung cancer.
Study identification
- NCT ID
- NCT02152631
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 453 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 3, 2014 (Actual)
- Primary completion
- Sep 15, 2017 (Actual)
- Completion
- Dec 2026 (Estimated)
- Last update posted
- Feb 6, 2026
2014 – 2026
United States locations
- U.S. sites
- 54
- U.S. states
- 29
- U.S. cities
- 42
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Highlands Oncology Group | Fayetteville | Arkansas | 72703 | — |
| St. Bernards Medical Center | Jonesboro | Arkansas | 72401 | — |
| City of Hope National Medical Center | Duarte | California | 91010 | — |
| University of California - San Diego | La Jolla | California | 92037 | — |
| Loma Linda University School of Medicine | Loma Linda | California | 92350 | — |
| CBCC Global Research, Inc. | Los Angeles | California | 90024 | — |
| Central Coast Medical Oncology Corporation | Los Angeles | California | 90024 | — |
| Fort Wayne Oncology & Hematology | Los Angeles | California | 90024 | — |
| SMO TRIO -Translational Research | Los Angeles | California | 90024 | — |
| St. Joseph Heritage Medical Group | Los Angeles | California | 90024 | — |
| UCLA Department of Medicine-Hematology/Oncology | Los Angeles | California | 90024 | — |
| Cancer Care Associates Medical Group | Los Angeles | California | 90095 | — |
| Dignity Health Care Institute | Sacramento | California | 95816 | — |
| Alegent Immanuel Cancer Center | Englewood | Colorado | 80112 | — |
| Jewish Hospital | Englewood | Colorado | 80112 | — |
| Oncology Hematology West | Englewood | Colorado | 80112 | — |
| SMO Catholic Health Initiatives | Englewood | Colorado | 80112 | — |
| St Joseph Cancer Center | Englewood | Colorado | 80112 | — |
| St. Francis Medical Center | Englewood | Colorado | 80112 | — |
| Medical Oncology Hematology Consultants | Newark | Delaware | 19713 | — |
| Boca Raton Regional Hospital | Boca Raton | Florida | 33486 | — |
| Halifax Medical Center | Daytona Beach | Florida | 32114 | — |
| Memorial Cancer Institute | Pembroke Pines | Florida | 33028 | — |
| H Lee Moffitt Cancer Center | Tampa | Florida | 33612-9497 | — |
| University Cancer & Blood Center, LLC | Athens | Georgia | 30607 | — |
| Ingalls Memorial Hospital | Harvey | Illinois | 60426 | — |
| Indiana University School of Medicine | Indianapolis | Indiana | 46202 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| Cancer Center of Kansas, P.A. | Wichita | Kansas | 67214 | — |
| Central Baptist Hospital | Lexington | Kentucky | 40503 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| Walter Reed National Military Medical Center | Bethesda | Maryland | 20889 | — |
| Metro-West and Greater Boston CNS Research | Framingham | Massachusetts | 01701 | — |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Mercy Medical Research Institute | Springfield | Missouri | 65807 | — |
| Billings Clinic Research Center | Billings | Montana | 59101 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Broome Oncology | Johnson City | New York | 13790 | — |
| Weill Cornell Medical College | New York | New York | 10065 | — |
| Oncology Hematology Care Inc | Cincinnati | Ohio | 45242 | — |
| Oklahoma Cancer Specialists & Research Institute, LLC | Tulsa | Oklahoma | 74146 | — |
| Providence Cancer Center Oncology Hematology Care | Portland | Oregon | 97213 | — |
| UPMC Hillman Cancer Center | Pittsburgh | Pennsylvania | 15213 | — |
| Roper St. Francis Healthcare | Charleston | South Carolina | 29401 | — |
| Chattanooga Oncology Hematology Associates | Chattanooga | Tennessee | 37404 | — |
| Chattanooga Oncology Hematology Associates | Nashville | Tennessee | 37203 | — |
| Tennessee Oncology PLLC | Nashville | Tennessee | 37203 | — |
| Mary Crowley Cancer Research Center | Dallas | Texas | 75230 | — |
| Utah Cancer Specialists | Salt Lake City | Utah | 84106 | — |
| University of Vermont Medical Center | Burlington | Vermont | 05401 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
| Kadlec Clinical Hematology & Oncology | Kennewick | Washington | 99336 | — |
| Swedish Medical Center | Seattle | Washington | 98104 | — |
| Cancer Care Northwest | Valley | Washington | 99216 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 177 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02152631, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 6, 2026 · Synced Oct 30, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02152631 live on ClinicalTrials.gov.