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Active, not recruiting Phase 1Phase 2 Interventional Results available

Study of Acalabrutinib Alone or in Combination Therapy in Subjects With B-cell Non-Hodgkin Lymphoma

ClinicalTrials.gov ID: NCT02180711

Public ClinicalTrials.gov record NCT02180711. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 30, 2026, 1:24 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-label, Phase 1b/2 Study of Acalabrutinib Alone or in Combination Therapy in Subjects With B-cell Non-Hodgkin Lymphoma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Part 1: To characterize the safety profile of acalabrutinib alone or in combination with rituximab in subjects with R/R FL. Part 2: To characterize the activity of acalabrutinib alone or in combination with rituximab in subjects with R/R MZL, as measured by ORR. Part 3: To characterize the safety of acalabrutinib in combination with rituximab and lenalidomide in subjects with R/R FL

Study identification

NCT ID
NCT02180711
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Acerta Pharma BV
Industry
Enrollment
113 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 29, 2014 (Actual)
Primary completion
Aug 25, 2023 (Actual)
Completion
Dec 11, 2028 (Estimated)
Last update posted
Sep 28, 2026

2014 – 2028

United States locations

U.S. sites
23
U.S. states
14
U.S. cities
21
Facility City State ZIP Site status
Research Site Tucson Arizona 85719 —
Research Site Downey California 90241 —
Research Site Duarte California 91010 —
Research Site Fountain Valley California 92708 —
Research Site Santa Monica California 90404 —
Research Site Coral Gables FL Florida 33146 —
Research Site Chicago Illinois 60611 —
Research Site Chicago Illinois 60612 —
Research Site Chicago Illinois 60637 —
Research Site Louisville Kentucky 40207 —
Research Site New Orleans Louisiana 70112 —
Research Site Ann Arbor Michigan 48109 —
Research Site Morristown New Jersey 07960 —
Research Site Lake Success New York 11042 —
Research Site New York New York 10021 —
Research Site Columbus Ohio 43210 —
Research Site Greenville South Carolina 29615 —
Research Site Dallas Texas 75235 —
Research Site Houston Texas 77030 —
Research Site San Antonio Texas 78217 —
Research Site Temple Texas 76508 —
Research Site Salt Lake City Utah 84112 —
Research Site Spokane Washington 99208 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02180711, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 28, 2026 · Synced Sep 30, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02180711 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →