ClinicalTrials.gov record
LEE011 for Patients With CDK4/6 Pathway Activated Tumors (SIGNATURE)
ClinicalTrials.gov ID: NCT02187783
Public ClinicalTrials.gov record NCT02187783. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Modular Phase II Study to Link Targeted Therapy to Patients With Pathway Activated Tumors: Module 8 - LEE011 for Patients With CDK4/6 Pathway Activated Tumors
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this signal seeking study was to determine whether treatment with LEE011 demonstrates sufficient efficacy in CDK4/6 pathway activated solid tumors and/or hematologic malignancies to warrant further study.
Study identification
- NCT ID
- NCT02187783
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 106 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 25, 2014 (Actual)
- Primary completion
- Jan 17, 2018 (Actual)
- Completion
- Jan 17, 2018 (Actual)
- Last update posted
- Jul 18, 2019
2014 – 2018
United States locations
- U.S. sites
- 61
- U.S. states
- 34
- U.S. cities
- 56
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35249 | — |
| Alaska Clinical Research | Anchorage | Alaska | 99503 | — |
| Arizona Oncology Associates Dept. Of Onc. | Phoenix | Arizona | — | — |
| University of Arkansas/ Arkansas Cancer Research Center UA Medical Sciences | Little Rock | Arkansas | 72205 | — |
| PCR Oncology | Pismo Beach | California | 93449 | — |
| University of California Davis Cancer Center UC Davis Cancer (3) | Sacramento | California | 95817 | — |
| Sarah Cannon Research Institute | Denver | Colorado | 80218 | — |
| Danbury Hospital | Danbury | Connecticut | 06810 | — |
| Yale University School of Medicine Smilow Cancer Hospital | New Haven | Connecticut | 06520 | — |
| Whittingham Cancer Center Norwalk Hospital | Norwalk | Connecticut | 06856 | — |
| Stamford Hospital Med. Oncology Hematology Res. | Stamford | Connecticut | 06902 | — |
| Florida Hospital Cancer Institute | Orlando | Florida | 32804 | — |
| NorthWest Georgia Oncology Centers NW Georgia Oncology | Marietta | Georgia | 30060 | — |
| Harbin Clinic Medical Oncology Clin. Res. | Rome | Georgia | 30165 | — |
| Queen's Medical Center Queens Cancer Center | Honolulu | Hawaii | 96817 | — |
| Northwestern Medicine Developmental Therapeutics Institute | Chicago | Illinois | 60611 | — |
| Indiana University Indiana Univ. - Purdue Univ. | Indianapolis | Indiana | 46202 | — |
| Northern Indiana Cancer Research Consortium No. Indiana Cancer Res. | South Bend | Indiana | 46617 | — |
| University of Iowa Hospitals & Clinics Regulatory Contact 2 | Iowa City | Iowa | 52242 | — |
| New England Cancer Specialists | Scarborough | Maine | 04074 | — |
| St. Agnes Hospital St. Agnes Hospital (2) | Baltimore | Maryland | 21229 | — |
| Michigan Medicine University of Michigan Int. Medicine Oncology | Ann Arbor | Michigan | 48109 5271 | — |
| Cancer and Hematology Centers of West Michigan Dept. of Oncology | Grand Rapids | Michigan | 49546 | — |
| Saint Luke's Hospital/Marion Bloch Neuroscience Institute St. Luke's Hospital (4) | Kansas City | Missouri | 64111 | — |
| Research Medical Center Research Med Center (2) | Kansas City | Missouri | 64132 | — |
| Comprehensive Cancer Centers of Nevada CCC of Nevada- Southwest (2) | Las Vegas | Nevada | 89109 | — |
| Cooper Health System Cooper Health System (5) | Camden | New Jersey | 08103 | — |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08903 | — |
| New Mexico Cancer Care Alliance | Albuquerque | New Mexico | 87106 | — |
| Cancer Center at Presbyterian | Albuquerque | New Mexico | — | — |
| Broome Oncology Broome Oncology (2) | Johnson City | New York | 13790 | — |
| University of N C at Chapel Hill Physician Office Building | Chapel Hill | North Carolina | 27599-7600 | — |
| Carolina Oncology Specialists, PC | Hickory | North Carolina | 28602 | — |
| Wake Forest University Baptist Medical Center | Winston-Salem | North Carolina | 27157 | — |
| Oncology Hematology Care Inc Oncology Hematology Care 2 | Cincinnati | Ohio | 45242 | — |
| Cleveland Clinic Foundation Taussig Cancer Institute | Cleveland | Ohio | 44195 | — |
| Ohio State University Medical Center Comprehensive Cancer Center | Columbus | Ohio | 43221 | — |
| Oregon Health and Science University Oregon Health & Science U (56) | Portland | Oregon | 97239 | — |
| Salem Health | Salem | Oregon | 97309 | — |
| Fox Chase Cancer Center Dept of Medical Oncology | Philadelphia | Pennsylvania | 19111 | — |
| Rhode Island Hospital Rhode Island Hosp. (2) | Providence | Rhode Island | 02903 | — |
| Greenville Health System ITOR - Cancer Institute | Greenville | South Carolina | 29615 | — |
| Sanford University of South Dakota Medical Center Sanford Health | Sioux Falls | South Dakota | 57104 | — |
| Chattanooga Oncology and Hematology Assoicates, PC Chattanooga Oncology | Chattanooga | Tennessee | 37404 | — |
| The West Clinic Dept. of the West Clinic | Memphis | Tennessee | 38120 | — |
| Tennessee Oncology Tennessee Oncology (3) | Nashville | Tennessee | 37203 | — |
| Coastal Bend Cancer Center | Corpus Christi | Texas | 78404 | — |
| Oncology Consultants Oncology Group | Houston | Texas | 77024 | — |
| MD Anderson Cancer Center/University of Texas MD Anderson Cancer Center (3) | Houston | Texas | 77030 | — |
| University of Texas Health Science Center at San Antonio Cancer Therapy & Research Ctr. | San Antonio | Texas | 78229 | — |
| Intermountain Medical Center Intermountain Healthcare | Murray | Utah | 84157 | — |
| Utah Cancer Specialists Utah Cancer Specialists (11) | Salt Lake City | Utah | 84106 | — |
| Shenandoah Oncology Shenadoah Oncology (2) | Winchester | Virginia | 22601 | — |
| Kadlec Clinic Hematology and Oncology Kadlec Clinic Hematology & Onc | Kennewick | Washington | 99336 | — |
| Vista Oncology Inc. PS | Olympia | Washington | 98502 | — |
| Multicare Research Institute | Tacoma | Washington | 98405 | — |
| Northwest Medical Specialties Rainier Physicians, PC | Tacoma | Washington | 98405 | — |
| Providence St. Mary Regional Cancer Center | Walla Walla | Washington | 98057 | — |
| Wenatchee Valley Medical Center Wenatchee Valley | Wenatchee | Washington | 98801 | — |
| Aurora Research Institute Aurora Health Care | Milwaukee | Wisconsin | 53226 | — |
| Medical College of Wisconsin Cancer Center | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02187783, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 18, 2019 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02187783 live on ClinicalTrials.gov.