YouScript IMPACT Registry
Public ClinicalTrials.gov record NCT02191358. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
YouScript IMPACT (Improving Medication Protocols and Abating Cost of Treatment) Registry
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This multicenter observational study aims to investigate the benefits of providing pharmacogenetic testing with the YouScript Personalized Prescribing System which includes a clinical decision support tool and individualized pharmacist recommendations to elderly polypharmacy patients who are most at risk of adverse drug events. The YouScript system is unique in identifying drug-gene, and drug-drug-gene interactions that are missed by existing systems, and represent over 35% of significant interaction warnings. Data analysis will assess the impact of recommendations for medication changes on clinical decision making, patient outcomes, and healthcare resource utilization to determine which medications, specialties, or patient segments derive the greatest benefit from this intervention. Data gathered from patients enrolled in this study will be compared to patients matched on key characteristics from Inovalon's MORE2 healthcare database.
Study identification
- NCT ID
- NCT02191358
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 800 participants
Conditions and interventions
Conditions
- Adverse Drug Events
- Adverse Drug Reactions
- Drug Interaction Potentiation
- Drug Metabolism, Poor, CYP2D6-RELATED
- Drug Metabolism, Poor, CYP2C19-RELATED
- Cytochrome P450 Enzyme Deficiency
- Cytochrome P450 CYP2D6 Enzyme Deficiency
- Cytochrome P450 CYP2C9 Enzyme Deficiency
- Cytochrome P450 CYP2C19 Enzyme Deficiency
- Cytochrome P450 CYP3A Enzyme Deficiency
- Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant
- Poor Metabolizer Due to Cytochrome P450 CYP2C19 Variant
- Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 65 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 30, 2014
- Primary completion
- Jul 31, 2015
- Completion
- Jul 31, 2015
- Last update posted
- Feb 28, 2017
2014 – 2015
United States locations
- U.S. sites
- 7
- U.S. states
- 6
- U.S. cities
- 6
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Dr. Michael Dao | Garden Grove | California | 92844 | — |
| Kaiser Permanente Colorado | Denver | Colorado | 80011 | — |
| Gill Heart Institute | Lexington | Kentucky | 40508 | — |
| IRC Clinics | Towson | Maryland | 21204 | — |
| Internal Medicine & Cardiology Associates | Fall River | Massachusetts | 02720 | — |
| Prima CARE | Fall River | Massachusetts | 02720 | — |
| Carilion Clinic | Christiansburg | Virginia | 24073 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02191358, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 28, 2017 · Synced Sep 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02191358 live on ClinicalTrials.gov.