LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis
Public ClinicalTrials.gov record NCT02205762. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The LCH-IV is an international, multicenter, prospective clinical study for pediatric Langerhans Cell Histiocytosis LCH (age \< 18 years).
Study identification
- NCT ID
- NCT02205762
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 1,400 participants
Conditions and interventions
Conditions
Interventions
- Prednisone Drug
- Vinblastine Drug
- mercaptopurine Drug
- INDOMETHACIN Drug
- Methotrexate Drug
- Cytosine Arabinoside Drug
- 2-chlorodeoxyadenosine Drug
- hematopoietic stem cell transplantation (RIC-HSCT) Procedure
- Intravenous immunoglobulin Biological
Drug · Procedure · Biological
Eligibility (public fields only)
- Age range
- Up to 18 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 2, 2016 (Type not available)
- Primary completion
- Jul 2026 (Estimated)
- Completion
- Jul 2026 (Estimated)
- Last update posted
- Apr 9, 2026
2016 – 2026
United States locations
- U.S. sites
- 42
- U.S. states
- 25
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Children's of Alabama | Birmingham | Alabama | 35233 | — |
| Phoenix Children's Hospital | Phoenix | Arizona | 85006 | — |
| Arkansas Children's Hospital | Little Rock | Arkansas | 72202 | — |
| Children's Hospital of Los Angeles | Los Angeles | California | 90027 | — |
| Valley Children's Healthcare | Madera | California | 93636 | — |
| UCSF Benioff Children's Hospital of Oakland | Oakland | California | 94609 | — |
| Children's Hospital of Orange County | Orange | California | 92868 | — |
| UCSF Helen Diller Family Cancer Center | San Francisco | California | 94158-0106 | — |
| Connecticut Children's Medical Center | Hartford | Connecticut | 06106 | — |
| Children's National Medical Center | Washington D.C. | District of Columbia | 20010 | — |
| Johns Hopkins All Children's Hospital | St. Petersburg | Florida | 33701 | — |
| Children's Healthcare of Atlanta, Emory | Atlanta | Georgia | 30342 | — |
| Ann & Robert H. Lurie Children's Hospital of Chicago | Chicago | Illinois | 60611-2991 | — |
| Riley Hospital for Children - Indiana University | Indianapolis | Indiana | 46202 | — |
| Children's Mercy Hospitals | Kansas City | Kansas | 64108 | — |
| University of Kentucky A.B.Chandler Medical Center | Lexington | Kentucky | 40536 | — |
| University of Louisville, Norton Children's Hospital | Louisville | Kentucky | 40202 | — |
| Johns Hopkins University | Baltimore | Maryland | 21287 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| Children's Minnesota | Minneapolis | Minnesota | 55404 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Cohen Children's Medical Center | New Hyde Park | New York | 11040 | — |
| Mount Sinai Hospital | New York | New York | 10029 | — |
| Columbia University / Herbert Irving Cancer Center | New York | New York | 10032 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10170 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| Children's Hospital at Montefiore | The Bronx | New York | 10467 | — |
| Carolinas Medical Center, Levine Children's Hospital | Charlotte | North Carolina | 28203 | — |
| Akron Children's Hospital | Akron | Ohio | 44308 | — |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | — |
| Rainbow Babies & Children's Hospital, University Hospitals | Cleveland | Ohio | 44106 | — |
| Russell J Ebeid Children's Hospital (Promedica) | Toledo | Ohio | 43606 | — |
| UPMC Children's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15224 | — |
| Medical University of South Carolina (MUSC) | Charleston | South Carolina | 29425 | — |
| Greenville Health System BI-LO Charities Children's Cancer Center | Greenville | South Carolina | 29605 | — |
| St. Jude Children's Research Hospital | Memphis | Tennessee | 38105 | — |
| Vanderbilt-Ingram Cancer Center | Nashville | Tennessee | 37232 | — |
| Children's Medical Center Dallas, UT Southwestern | Dallas | Texas | 75235 | — |
| Providence Sacred Heart Children's Hospital | Spokane | Washington | 99204 | — |
| Madigan Army Medical Center | Tacoma | Washington | 98431 | — |
| American Family Children's Hospital University of Wisconsin | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02205762, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 9, 2026 · Synced Oct 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02205762 live on ClinicalTrials.gov.