ClinicalTrials.gov record
Active, not recruiting Phase 2Phase 3 Interventional

LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis

ClinicalTrials.gov ID: NCT02205762

Public ClinicalTrials.gov record NCT02205762. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 22, 2026, 5:56 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Study identification

NCT ID
NCT02205762
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
North American Consortium for Histiocytosis
Other
Enrollment
1,400 participants

Conditions and interventions

Interventions

  • 2-chlorodeoxyadenosine Drug
  • Cytosine Arabinoside Drug
  • INDOMETHACIN Drug
  • Intravenous immunoglobulin Biological
  • Methotrexate Drug
  • Prednisone Drug
  • Vinblastine Drug
  • hematopoietic stem cell transplantation (RIC-HSCT) Procedure
  • mercaptopurine Drug

Drug · Biological · Procedure

Eligibility (public fields only)

Age range
Up to 18 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 1, 2016
Primary completion
Jun 30, 2026
Completion
Jun 30, 2026
Last update posted
Apr 8, 2026

2016 – 2026

United States locations

U.S. sites
42
U.S. states
25
U.S. cities
39
Facility City State ZIP Site status
Children's of Alabama Birmingham Alabama 35233
Phoenix Children's Hospital Phoenix Arizona 85006
Arkansas Children's Hospital Little Rock Arkansas 72202
Children's Hospital of Los Angeles Los Angeles California 90027
Valley Children's Healthcare Madera California 93636
UCSF Benioff Children's Hospital of Oakland Oakland California 94609
Children's Hospital of Orange County Orange California 92868
UCSF Helen Diller Family Cancer Center San Francisco California 94158-0106
Connecticut Children's Medical Center Hartford Connecticut 06106
Children's National Medical Center Washington D.C. District of Columbia 20010
Johns Hopkins All Children's Hospital St. Petersburg Florida 33701
Children's Healthcare of Atlanta, Emory Atlanta Georgia 30342
Ann & Robert H. Lurie Children's Hospital of Chicago Chicago Illinois 60611-2991
Riley Hospital for Children - Indiana University Indianapolis Indiana 46202
Children's Mercy Hospitals Kansas City Kansas 64108
University of Kentucky A.B.Chandler Medical Center Lexington Kentucky 40536
University of Louisville, Norton Children's Hospital Louisville Kentucky 40202
Johns Hopkins University Baltimore Maryland 21287
Massachusetts General Hospital Boston Massachusetts 02114
Dana Farber Cancer Institute Boston Massachusetts 02115
Children's Minnesota Minneapolis Minnesota 55404
Hackensack University Medical Center Hackensack New Jersey 07601
Cohen Children's Medical Center New Hyde Park New York 11040
Mount Sinai Hospital New York New York 10029
Columbia University / Herbert Irving Cancer Center New York New York 10032
Memorial Sloan Kettering Cancer Center New York New York 10170
SUNY Upstate Medical University Syracuse New York 13210
Children's Hospital at Montefiore The Bronx New York 10467
Carolinas Medical Center, Levine Children's Hospital Charlotte North Carolina 28203
Akron Children's Hospital Akron Ohio 44308
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229
Rainbow Babies & Children's Hospital, University Hospitals Cleveland Ohio 44106
Russell J Ebeid Children's Hospital (Promedica) Toledo Ohio 43606
UPMC Children's Hospital of Pittsburgh Pittsburgh Pennsylvania 15224
Medical University of South Carolina (MUSC) Charleston South Carolina 29425
Greenville Health System BI-LO Charities Children's Cancer Center Greenville South Carolina 29605
St. Jude Children's Research Hospital Memphis Tennessee 38105
Vanderbilt-Ingram Cancer Center Nashville Tennessee 37232
Children's Medical Center Dallas, UT Southwestern Dallas Texas 75235
Providence Sacred Heart Children's Hospital Spokane Washington 99204
Madigan Army Medical Center Tacoma Washington 98431
American Family Children's Hospital University of Wisconsin Madison Wisconsin 53792

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02205762, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 8, 2026 · Synced Apr 22, 2026

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Open the official record

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