Genetically Modified T-cells in Treating Patients With Recurrent or Refractory Malignant Glioma
Public ClinicalTrials.gov record NCT02208362. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase I Study of Cellular ImmunoTx Using Memory Enriched T Cells Lentivirally Transduced to Express an IL13Rα2-Specific, Hinge-Optimized, 41BB-Costimulatory Chimeric Receptor and a Truncated CD19 for Pts With Rec/Ref MaligGlioma
Study identification
- NCT ID
- NCT02208362
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- City of Hope Medical Center
- Other
- Enrollment
- 65 participants
Conditions and interventions
Conditions
Interventions
- Arm 1: IL13Ra2-specific CAR Tcm cells Biological
- Arm 2: IL13Ra2-specific CAR Tcm cells Biological
- Arm 3: IL13Ra2-specific CAR Tcm cells Biological
- Arm 4: IL13Ra2-specific CAR Tcm cells Biological
- Arm 5: IL13Ra2-specific CAR Tn/mem cells Biological
- Laboratory Biomarker Analysis Other
- Magnetic Resonance Imaging Procedure
- Magnetic Resonance Spectroscopic Imaging Procedure
- Quality-of-Life Assessment Other
Biological · Other · Procedure
Eligibility (public fields only)
- Age range
- 12 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 17, 2015
- Primary completion
- Feb 7, 2021
- Completion
- Jun 7, 2026
- Last update posted
- Sep 2, 2025
2015 – 2026
United States locations
- U.S. sites
- 1
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| City of Hope Medical Center | Duarte | California | 91010 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02208362, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 2, 2025 · Synced May 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02208362 live on ClinicalTrials.gov.