ClinicalTrials.gov record
An Efficacy and Safety Study of Lanabecestat (LY3314814) in Early Alzheimer's Disease
ClinicalTrials.gov ID: NCT02245737
Public ClinicalTrials.gov record NCT02245737. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 21, 2026, 1:18 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 24-month, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Efficacy, Safety, Tolerability, Biomarker, and Pharmacokinetic Study of AZD3293 in Early Alzheimer's Disease (The AMARANTH Study)
Study identification
- NCT ID
- NCT02245737
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Lead sponsor
- AstraZeneca
- Industry
- Enrollment
- 2,218 participants
Conditions and interventions
Conditions
Interventions
- Lanabecestat Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 55 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 29, 2014
- Primary completion
- Oct 3, 2018
- Completion
- Oct 3, 2018
- Last update posted
- Dec 2, 2019
2014 – 2018
United States locations
- U.S. sites
- 77
- U.S. states
- 24
- U.S. cities
- 61
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner Alzheimer's Institute | Phoenix | Arizona | 85006 | — |
| St Josephs Hospital and Medical Center | Phoenix | Arizona | 85013 | — |
| Banner Sun Health Research Institute | Sun City | Arizona | 85351 | — |
| Territory Neurology & Research Institute | Tucson | Arizona | 85704 | — |
| Positron Research International | Fremont | California | 94538 | — |
| Alliance Research Centers | Laguna Hills | California | 92653 | — |
| Senior Clinical Trials, Inc. | Laguna Hills | California | 92653 | — |
| Collaborative Neuroscience Network - CNS | Long Beach | California | 90806 | — |
| Pacific Research Network Inc | San Diego | California | 92103 | — |
| San Francisco Clinical Research Center | San Francisco | California | 94109 | — |
| Mile High Research Center | Denver | Colorado | 80218 | — |
| Institute for Neurodegenerative Disorders | New Haven | Connecticut | 06510 | — |
| Georgetown University Medical Center | Washington D.C. | District of Columbia | 20057 | — |
| Brain Matters Research | Delray Beach | Florida | 33445 | — |
| Direct Helpers Medical Center | Hialeah | Florida | 33012 | — |
| Berma Research | Hialeah | Florida | 33016 | — |
| Galiz Research | Hialeah | Florida | 33016 | — |
| MaxBlue Institute | Hialeah | Florida | 33018 | — |
| Alzheimer's Research and Treatment Center | Lake Worth | Florida | 33449 | — |
| Miami Jewish Health Systems | Miami | Florida | 33137 | — |
| Medical Research Center | Miami | Florida | 33144 | — |
| Allied Biomedical Research Institute, Inc. | Miami | Florida | 33155 | — |
| Advance Medical Research Institute | Miami | Florida | 33174 | — |
| New Horizon Research Center | Miami | Florida | 33175 | — |
| JDH Medical Group, LLC | Miami | Florida | 33186 | — |
| Compass Research | Orlando | Florida | 32806 | — |
| IMIC, Inc. | Palmetto Bay | Florida | 33157 | — |
| Roskamp Institute | Sarasota | Florida | 34243 | — |
| Suncoast Neuroscience Associates | St. Petersburg | Florida | 33713 | — |
| Infinity Clinical Research, LLC | Sunrise | Florida | 33351 | — |
| Stedman Clinical Trials | Tampa | Florida | 33613 | — |
| Olympian Clinical Research | Tampa | Florida | 33614 | — |
| Compass Research | The Villages | Florida | 32162 | — |
| Premiere Research Institute at Palm Beach Neurology | West Palm Beach | Florida | 33407 | — |
| The Multiple Sclerosis Center of Atlanta | Atlanta | Georgia | 30327 | — |
| Atlanta Center of Medical Research | Atlanta | Georgia | 30331 | — |
| Carman Research | Smyrna | Georgia | 30080 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Alexian Brothers Medical Center | Elk Grove Village | Illinois | 60007 | — |
| Community Clinical Research Center | Anderson | Indiana | 46011 | — |
| Indiana University School of Medicine | Indianapolis | Indiana | 46202 | — |
| ActivMed Practices & Research, Inc | Methuen | Massachusetts | 01844 | — |
| Boston Center for Memory | Newton | Massachusetts | 02459 | — |
| Springfield Neurology Associates | Springfield | Massachusetts | 01104 | — |
| Hattiesburg Clinic | Hattiesburg | Mississippi | 39401 | — |
| Millennium Psychiatric Associates, LLV | St Louis | Missouri | 63141 | — |
| St. Louis Clinical Trials, LC | St Louis | Missouri | 63141 | — |
| Memory Enhancement Center of America, Inc. | Eatontown | New Jersey | 07724 | — |
| AdvanceMed Research | Lawrenceville | New Jersey | 08648 | — |
| Alzheimer's Research Company | Paterson | New Jersey | 08759 | — |
| The Cognitive and Research Center of NJ | Springfield | New Jersey | 07081 | — |
| Advanced Memory Research Institute of New Jersey | Toms River | New Jersey | 08755 | — |
| Bio Behavioral Health | Toms River | New Jersey | 08755 | — |
| Neurology Specialists of Monmouth County | West Long Branch | New Jersey | 07764 | — |
| Integrative Clinical Trials, LLC | Brooklyn | New York | 11229 | — |
| SPRI Clinical Trials, LLC. | Brooklyn | New York | 11235 | — |
| Alzheimer's Disease and Memory Disorders Center | Buffalo | New York | 14203 | — |
| Empire Neurology, PC | Latham | New York | 12110 | — |
| Clinilabs, Inc (New York) | New York | New York | 10019 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| University of Rochester | Rochester | New York | 14620 | — |
| Alzheimer's Memory Center | Charlotte | North Carolina | 28270 | — |
| Valley Medical Primary Care | Centerville | Ohio | 45459 | — |
| Christ Hospital | Cincinnati | Ohio | 45219 | — |
| Ohio State University Medical Center | Columbus | Ohio | 43221 | — |
| The Corvallis Clinic P.C. | Corvallis | Oregon | 97330 | — |
| Lehigh Valley Hospital | Allentown | Pennsylvania | 18103 | — |
| Rhode Island Mood & Memory Research Institute | East Providence | Rhode Island | 02914 | — |
| Roper St. Francis Healthcare | Charleston | South Carolina | 29401 | — |
| Radiant Research | Greer | South Carolina | 29651 | — |
| Quillen College of Medicine, East TN State University | Johnson City | Tennessee | 37605 | — |
| Senior Adults Specialty Research Inc | Austin | Texas | 78757 | — |
| Texas Health Physicians Group | Dallas | Texas | 75231 | — |
| Medical Group of Texas | Fort Worth | Texas | 76104 | — |
| University of Texas Health Services Center - Houston | Houston | Texas | 77054 | — |
| University of Utah School of Medicine | Salt Lake City | Utah | 84108 | — |
| The Memory Clinic | Bennington | Vermont | 05201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 177 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02245737, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 2, 2019 · Synced May 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02245737 live on ClinicalTrials.gov.