ClinicalTrials.gov record
Completed Phase 1Phase 2 Interventional Results available

Dose Escalation Study in Patients With Relapsed or Refractory DLBCL and MyD88 L265P Mutation

ClinicalTrials.gov ID: NCT02252146

Public ClinicalTrials.gov record NCT02252146. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 4, 2026, 10:19 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase I/II Open-label, Multiple-dose, Dose-escalation Study to Evaluate the Safety and Tolerability of IMO-8400 in Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma and Presence of the MyD88 L265P Mutation

Study identification

NCT ID
NCT02252146
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Idera Pharmaceuticals, Inc.
Industry
Enrollment
6 participants

Conditions and interventions

Interventions

  • IMO-8400 Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 31, 2014
Primary completion
Nov 30, 2016
Completion
Nov 30, 2016
Last update posted
Dec 11, 2017

2014 – 2016

United States locations

U.S. sites
12
U.S. states
12
U.S. cities
12
Facility City State ZIP Site status
UCLA Medical Center Los Angeles California 90095
Emory University Atlanta Georgia 30306
Cancer Care Specialists of Illinois Decatur Illinois 62526
Horizon Bio Advance Lafayette Indiana 47905
Dana-Farber Cancer Institute Boston Massachusetts 02215
Mayo Clinic Rochester Minnesota 55905
Washington University St Louis Missouri 63110
Hackensack University Medical Center Hackensack New Jersey 07601
Columbia University Medical Center New York New York 10019
Cleveland Clinic Cleveland Ohio 44109
Vanderbilt Ingram Cancer Center Nashville Tennessee 37232
MD Anderson Cancer Center Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02252146, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 11, 2017 · Synced May 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02252146 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →