A Study to Learn About the Effects and Safety of RTA 408 (Omaveloxolone) in People Aged 16 to 40 With Friedreich's Ataxia
Public ClinicalTrials.gov record NCT02255435. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Study of the Safety, Efficacy, and Pharmacodynamics of RTA 408 in the Treatment of Friedreich's Ataxia (MOXIe)
Study identification
- NCT ID
- NCT02255435
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Biogen
- Industry
- Enrollment
- 172 participants
Conditions and interventions
Conditions
Interventions
- Omaveloxolone Capsules, 10 mg Drug
- Omaveloxolone Capsules, 150 mg Drug
- Omaveloxolone Capsules, 160 mg Drug
- Omaveloxolone Capsules, 2.5 mg Drug
- Omaveloxolone Capsules, 20 mg Drug
- Omaveloxolone Capsules, 300 mg Drug
- Omaveloxolone Capsules, 40 mg Drug
- Omaveloxolone Capsules, 5 mg Drug
- Omaveloxolone Capsules, 80 mg Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 16 Years to 40 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 30, 2015
- Primary completion
- Oct 30, 2019
- Completion
- Dec 18, 2025
- Last update posted
- Jan 22, 2026
2015 – 2025
United States locations
- U.S. sites
- 7
- U.S. states
- 6
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCLA | Los Angeles | California | 90095 | — |
| University of Florida - Neurology | Gainesville | Florida | 32610 | — |
| USF Ataxia Research Center | Tampa | Florida | 33612 | — |
| Emory University Hospital - Neurology | Atlanta | Georgia | 30329 | — |
| University of Iowa Stead Family Children's Hospital | Iowa City | Iowa | 52242 | — |
| Ohio State University - Neurology | Columbus | Ohio | 43221 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02255435, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 22, 2026 · Synced May 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02255435 live on ClinicalTrials.gov.