Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors
Public ClinicalTrials.gov record NCT02255461. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase I Study of CDK 4-6 Inhibitor PD-0332991 (Palbociclib; IBRANCE) in Children With Recurrent, Progressive or Refractory Central Nervous System Tumors
Study identification
- NCT ID
- NCT02255461
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Pediatric Brain Tumor Consortium
- Network
- Enrollment
- 35 participants
Conditions and interventions
Conditions
- Childhood Choroid Plexus Tumor
- Childhood Ependymoblastoma
- Childhood Grade III Meningioma
- Childhood High-grade Cerebellar Astrocytoma
- Childhood High-grade Cerebral Astrocytoma
- Childhood Medulloepithelioma
- Recurrent Childhood Anaplastic Astrocytoma
- Recurrent Childhood Anaplastic Oligoastrocytoma
- Recurrent Childhood Anaplastic Oligodendroglioma
- Recurrent Childhood Brain Stem Glioma
- Recurrent Childhood Cerebellar Astrocytoma
- Recurrent Childhood Cerebral Astrocytoma
- Recurrent Childhood Giant Cell Glioblastoma
- Recurrent Childhood Glioblastoma
- Recurrent Childhood Gliomatosis Cerebri
- Recurrent Childhood Gliosarcoma
- Recurrent Childhood Medulloblastoma
- Recurrent Childhood Pineoblastoma
- Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor
Interventions
- laboratory biomarker analysis Other
- palbociclib isethionate Drug
- pharmacological study Other
Other · Drug
Eligibility (public fields only)
- Age range
- 4 Years to 21 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 7, 2014
- Primary completion
- Feb 24, 2019
- Completion
- Feb 24, 2019
- Last update posted
- Mar 1, 2021
2014 – 2019
United States locations
- U.S. sites
- 11
- U.S. states
- 10
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Childrens Hospital Los Angeles | Los Angeles | California | 90027 | — |
| Lucile Packard Children Hospital Stanford University | Palo Alto | California | 94304 | — |
| Childrens National Medical Center | Washington D.C. | District of Columbia | 20010-2970 | — |
| Lurie Childrens Hospital-Chicago | Chicago | Illinois | 60614 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Cincinnati Children Hospital Medical Center | Cincinnati | Ohio | 45229 | — |
| Children Hospital of Pittsburgh of UPMC | Pittsburgh | Pennsylvania | 15224 | — |
| St. Jude Children Research Hospital | Memphis | Tennessee | 38105 | — |
| Texas Childrens Hospital | Houston | Texas | 77030 | — |
| Seattle Children Hospital | Seattle | Washington | 98105 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02255461, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 1, 2021 · Synced May 19, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02255461 live on ClinicalTrials.gov.