Testosterone Revival Abolishes Negative Symptoms, Fosters Objective Response and Modulates Enzalutamide Resistance
Public ClinicalTrials.gov record NCT02286921. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Phase II Study Comparing Bipolar Androgen Therapy vs. Enzalutamide in Asymptomatic Men With Castration Resistant Metastatic Prostate Cancer
Study identification
- NCT ID
- NCT02286921
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- Other
- Enrollment
- 222 participants
Conditions and interventions
Interventions
- Enzalutamide Drug
- Testosterone Enanthate Drug
- Testosterone cypionate Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 31, 2014
- Primary completion
- Oct 25, 2018
- Completion
- Feb 20, 2020
- Last update posted
- Nov 5, 2020
2015 – 2020
United States locations
- U.S. sites
- 17
- U.S. states
- 16
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Unversity of Alabama | Birmingham | Alabama | 35294 | — |
| City of Hope | Duarte | California | 91010 | — |
| University of Colorado Cancer Center | Aurora | Colorado | 80045 | — |
| Sibley Memorial Hospital | Washington D.C. | District of Columbia | 20016 | — |
| Piedmont Cancer Institute | Atlanta | Georgia | 30318 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| University of Kansas Cancer Center | Kansas City | Kansas | 66160 | — |
| Tulane University Medical Center | New Orleans | Louisiana | 70112 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| SKCCC at Johns Hopkins | Baltimore | Maryland | 21205 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Neraska Cancer Specialists | Omaha | Nebraska | 68130 | — |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08901 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Allegheny Health Network | Pittsburgh | Pennsylvania | 15212 | — |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | — |
| University of Washing | Seattle | Washington | 98109 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02286921, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 5, 2020 · Synced May 13, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02286921 live on ClinicalTrials.gov.