The VITAL Amyloidosis Study, a Global Phase 3, Efficacy and Safety Study of NEOD001 in Patients With AL Amyloidosis
Public ClinicalTrials.gov record NCT02312206. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Multicenter, Double-Blind, Placebo-Controlled, 2-Arm, Efficacy and Safety Study of NEOD001 Plus Standard of Care Versus Placebo Plus Standard of Care in Subjects With Light Chain (AL) Amyloidosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multi-center, international, randomized, double-blind, placebo-controlled, two-arm efficacy and safety study in subjects newly diagnosed with AL amyloidosis. Subjects will remain on-study until study completion, which will occur when all primary endpoint events (all-cause mortality or cardiac hospitalizations) have been reached.
Study identification
- NCT ID
- NCT02312206
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 260 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 2015 (Type not available)
- Primary completion
- May 2018 (Actual)
- Completion
- May 2018 (Actual)
- Last update posted
- Nov 14, 2023
2015 – 2018
United States locations
- U.S. sites
- 32
- U.S. states
- 24
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Arizona | Scottsdale | Arizona | 85259 | — |
| City of Hope | Duarte | California | 91010 | — |
| Stanford Cancer Institute (SCI) | Stanford | California | 94305 | — |
| Colorado Blood Cancer Institute | Denver | Colorado | 80218 | — |
| Mayo Clinic | Jacksonville | Florida | 32224 | — |
| Sylvester Cancer Center, University of Miami | Miami | Florida | 33312 | — |
| Winship Cancer Institute of Emory University | Atlanta | Georgia | 30322 | — |
| Radiant Research Northwestern University | Chicago | Illinois | 60611 | — |
| University of Chicago Medicine | Chicago | Illinois | 60637 | — |
| Indiana University Cancer Center | Indianapolis | Indiana | 46202 | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | — | — |
| John Hopkins University School of Medicine | Baltimore | Maryland | 21205 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Boston University School of Medicine | Boston | Massachusetts | 02118 | — |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Washington University in Saint Louis | St Louis | Missouri | 63110 | — |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07112 | — |
| Columbia University - College of Physicians & Surgeons | New York | New York | 10032 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10065 | — |
| University of North Carolina Chapel Hill Comprehensive Cancer Center | Chapel Hill | North Carolina | 27599-1651 | — |
| Levine Cancer Institute | Charlotte | North Carolina | 28211 | — |
| Duke University Medical Center | Durham | North Carolina | 27705 | — |
| The Cleveland Clinic - Main Campus | Cleveland | Ohio | 44195 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburg - Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232-5505 | — |
| University of Texas; MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | — |
| University of Washington | Seattle | Washington | 98109 | — |
| Froedtert & Medical College of Wisconsin, Cancer Center-Froedtert Hospital | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 47 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02312206, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 14, 2023 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02312206 live on ClinicalTrials.gov.