ClinicalTrials.gov record
Completed Phase 1 Interventional Results available

Study Of OX40 Agonist PF-04518600 Alone And In Combination With 4-1BB Agonist PF-05082566

ClinicalTrials.gov ID: NCT02315066

Public ClinicalTrials.gov record NCT02315066. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 16, 2026, 3:06 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A PHASE 1, OPEN-LABEL, DOSE ESCALATION STUDY OF PF-04518600 AS A SINGLE AGENT AND IN COMBINATION WITH PF-05082566 IN PATIENTS WITH SELECTED LOCALLY ADVANCED OR METASTATIC CANCERS

Study identification

NCT ID
NCT02315066
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Pfizer
Industry
Enrollment
174 participants

Conditions and interventions

Conditions

Interventions

  • PF-04518600 Drug
  • PF-04518600 plus PF-05082566 Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 22, 2015
Primary completion
Nov 11, 2020
Completion
Nov 11, 2020
Last update posted
Apr 20, 2022

2015 – 2020

United States locations

U.S. sites
24
U.S. states
7
U.S. cities
12
Facility City State ZIP Site status
The Angeles Clinic And Research Institute, A Cedars-Sinai Affiliate Los Angeles California 90025
Keck Hospital of USC Los Angeles California 90033
LAC+USC Medical Center Los Angeles California 90033
USC/Norris Comprehensive Cancer Center Los Angeles California 90033
Ronald Regan Medical Center Los Angeles California 90095
UCLA Hematology & Oncology Clinic Los Angeles California 90095
Hoag Memorial Hospital Presbyterian Newport Beach California 92663
Medical Imaging Center of Southern California, Inc. Santa Monica California 90403
Santa Monica UCLA Hematology & Oncology Clinic Santa Monica California 90404
UConn Health, Pharmacy Farmington Connecticut 06030-2205
UConn Health, Neag Comprehensive Cancer Center Farmington Connecticut 06030
H. Lee Moffitt Cancer Center & Research Institute Tampa Florida 33612
Massachusetts General Hospital (MGH) Boston Massachusetts 02114
Brigham & Women's Hospital (BWH) Boston Massachusetts 02115
Beth Israel Deaconess Medical Center (BIDMC) Boston Massachusetts 02215
Dana-Farber Cancer Institute (DFCI) Boston Massachusetts 02215
Massachusetts General/Chelsea HealthCare Center Chelsea Massachusetts 02150
Mass General/North Shore Center for Outpatient Care Danvers Massachusetts 01923
Mass General West Waltham Massachusetts 02451
Columbia University Medical Center - Herbert Irving Pavilion New York New York 10032
Methodist Hospital-Pathology Houston Texas 77030
The University of Texas MD Anderson Cancer Center Houston Texas 77030
Seattle Cancer Care Alliance Seattle Washington 98109
University of Washington Medical Center Seattle Washington 98195

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02315066, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 20, 2022 · Synced May 16, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02315066 live on ClinicalTrials.gov.

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