Phase 2/3, Randomized, Double-Masked, Sham-Controlled Trial of QPI-1007 in Subjects With Acute Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)
Public ClinicalTrials.gov record NCT02341560. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2/3, Randomized, Double-Masked, Sham-Controlled Trial of QPI-1007 Delivered By Single or Multi-Dose Intravitreal Injection(s) to Subjects With Acute Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will determine the effect of QPI-1007 on visual function in subjects with recent-onset NAION and assess the safety and tolerability of intravitreal injections of QPI-1007 in this population. This study will also evaluate the structural changes in the retina following administration of QPI-1007.
Study identification
- NCT ID
- NCT02341560
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 732 participants
Conditions and interventions
Interventions
Drug · Other
Eligibility (public fields only)
- Age range
- 50 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 24, 2016 (Actual)
- Primary completion
- Jul 1, 2019 (Actual)
- Completion
- Jul 1, 2019 (Actual)
- Last update posted
- Jul 20, 2020
2016 – 2019
United States locations
- U.S. sites
- 44
- U.S. states
- 24
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arkansas Medical Center, Jones Eye Institute | Little Rock | Arkansas | 72205 | — |
| Loma Linda University Eye Institute | Loma Linda | California | 92354 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| NeuroEyeOrbit Institute | Los Angeles | California | 90048 | — |
| Stanford University | Palo Alto | California | 94303 | — |
| Unversity of California, Los Angeles (UCLA) | Pasadena | California | 91105 | — |
| University of Colorado Denver, Department of Neurology | Aurora | Colorado | 80045 | — |
| Retina Consultants of Southern Colorado, PC | Colorado Springs | Colorado | 80909 | — |
| The Eye Care Group | Waterbury | Connecticut | 06708 | — |
| Cape Coral Eye Center | Cape Coral | Florida | 33904 | — |
| University of Miami Miller School of Medicine/Bascom Palmer Eye Institute | Miami | Florida | 33136 | — |
| Sarasota Retina Institute | Sarasota | Florida | 34239 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| University of Illinois at Chicago, Department of Ophthalmology (MC 648) | Chicago | Illinois | 60612 | — |
| NorthShore University Healthsystem | Glenview | Illinois | 60026 | — |
| University of Kentucky, Department of Neurology | Lexington | Kentucky | 40536 | — |
| Greater Baltimore Medical Center | Baltimore | Maryland | 21204 | — |
| Bethesda Neurology, LLC | Bethesda | Maryland | 20852 | — |
| Massachusetts Eye and Ear Infirmary | Boston | Massachusetts | 02114 | — |
| Boston Medical Center | Boston | Massachusetts | 21118 | — |
| University of Michigan | Ann Arbor | Michigan | 48105 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Washington University in St. Louis | St Louis | Missouri | 63110 | — |
| University of Nebraska Medical Center and Truhlsen Eye Institute | Omaha | Nebraska | 68198 | — |
| Rutgers, New Jersey Medical School | Newark | New Jersey | 07103 | — |
| New York Eye and Ear Infirmary of Mount Sinai | New York | New York | 10003 | — |
| Cornell University School of Medicine | New York | New York | 10583 | — |
| University of Rochester, Flaum Eye Institute | Rochester | New York | 14642 | — |
| State University of New York at Stony Brook | Stony Brook | New York | 11794 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| Duke University Eye Center | Durham | North Carolina | 27705 | — |
| Raleigh Neurology Associates | Raleigh | North Carolina | 27607 | — |
| Cleveland Clinic, Cole Eye Institute | Cleveland | Ohio | 44195 | — |
| Dean McGee Eye Institute | Oklahoma City | Oklahoma | 73013 | — |
| University of Pennsylvania, Scheie Eye Institute | Philadelphia | Pennsylvania | 19104 | — |
| Retina Consultants of Charleston | Charleston | South Carolina | 29414 | — |
| University of Houston, Neuro-Ophth of Texas | Houston | Texas | 77025 | — |
| Houston Methodist Hospital, Blanton Eye Institute | Houston | Texas | 77030 | — |
| Foresight Studies | San Antonio | Texas | 78240 | — |
| University of Utah John A. Moran Eye Center | Salt Lake City | Utah | 84132 | — |
| University of Virginia Health Sciences Center | Charlottesville | Virginia | 22908 | — |
| Swedish Medical Center, CO/NOCNW | Seattle | Washington | 98104 | — |
| University of Washington Department of Ophthalmology | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 41 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02341560, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 20, 2020 · Synced Oct 28, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02341560 live on ClinicalTrials.gov.