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Completed Phase 1Phase 2 Interventional Results available

ACP-196 (Acalabrutinib) in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies

ClinicalTrials.gov ID: NCT02362035

Public ClinicalTrials.gov record NCT02362035. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 1:29 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1b/2 Proof-of-Concept Study of the Combination of ACP-196 (Acalabrutinib) and Pembrolizumab in Subjects With Hematologic Malignancies

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study is evaluating the safety, pharmacodynamics (PD), and efficacy of acalabrutinib and pembrolizumab in hematologic malignancies.

Study identification

NCT ID
NCT02362035
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Acerta Pharma BV
Industry
Enrollment
161 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 20, 2015 (Actual)
Primary completion
Jul 14, 2020 (Actual)
Completion
Oct 27, 2025 (Actual)
Last update posted
May 13, 2026

2015 – 2025

United States locations

U.S. sites
19
U.S. states
14
U.S. cities
19
Facility City State ZIP Site status
Research Site Tucson Arizona 85704 —
Research Site Los Angeles California 90095 —
Research Site Denver Colorado 80218 —
Research Site Washington D.C. District of Columbia 20007 —
Research Site Niles Illinois 60714 —
Research Site Boston Massachusetts 2215 —
Research Site Rochester Minnesota 55905-0001 —
Research Site Omaha Nebraska 68198-7680 —
Research Site Columbus Ohio 43210 —
Research Site Greenville South Carolina 29605 —
Research Site Nashville Tennessee 37203 —
Research Site Dallas Texas 75246 —
Research Site Houston Texas 77030 —
Research Site San Antonio Texas 78217 —
Research Site Tyler Texas 75702 —
Research Site Fairfax Virginia 22031 —
Research Site Roanoke Virginia 24014 —
Research Site Vancouver Washington 98684 —
Research Site Yakima Washington 98902 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02362035, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 13, 2026 · Synced Oct 21, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02362035 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →