Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy
Public ClinicalTrials.gov record NCT02432963. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase I Study of a p53MVA Vaccine in Combination With Pembrolizumab
Study identification
- NCT ID
- NCT02432963
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- City of Hope Medical Center
- Other
- Enrollment
- 11 participants
Conditions and interventions
Conditions
- Adult Solid Neoplasm
- Bladder Carcinoma
- Colon Carcinoma
- Estrogen Receptor Negative
- HER2/Neu Negative
- Head and Neck Squamous Cell Carcinoma
- Hepatocellular Carcinoma
- Melanoma
- Non-Small Cell Lung Carcinoma
- Pancreatic Carcinoma
- Progesterone Receptor Negative
- Rectal Carcinoma
- Renal Cell Carcinoma
- Soft Tissue Sarcoma
- TP53 Gene Mutation
- Triple-Negative Breast Carcinoma
- Unresectable Solid Neoplasm
Interventions
- Laboratory Biomarker Analysis Other
- Modified Vaccinia Virus Ankara Vaccine Expressing p53 Biological
- Pembrolizumab Biological
Other · Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 13, 2016
- Primary completion
- Dec 3, 2017
- Completion
- Oct 1, 2026
- Last update posted
- Jan 27, 2026
2016 – 2026
United States locations
- U.S. sites
- 1
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| City of Hope Medical Center | Duarte | California | 91010 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02432963, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 27, 2026 · Synced May 19, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02432963 live on ClinicalTrials.gov.