A Study of Atezolizumab Versus Observation as Adjuvant Therapy in Participants With High-Risk Muscle-Invasive Urothelial Carcinoma (UC) After Surgical Resection
Public ClinicalTrials.gov record NCT02450331. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Open-Label, Multicenter, Randomized Study of Atezolizumab (Anti-PD-L1 Antibody) Versus Observation as Adjuvant Therapy in Patients With High-Risk Muscle-Invasive Urothelial Carcinoma After Surgical Resection
Study identification
- NCT ID
- NCT02450331
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 809 participants
Conditions and interventions
Conditions
Interventions
- Atezolizumab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 4, 2015
- Primary completion
- Nov 29, 2019
- Completion
- Jun 13, 2022
- Last update posted
- Jun 17, 2023
2015 – 2022
United States locations
- U.S. sites
- 41
- U.S. states
- 19
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| HonorHealth Research Institute - Pima - Virginia G. Piper Cancer Care Network | Scottsdale | Arizona | 85258 | — |
| UCLA | Los Angeles | California | 90024 | — |
| USC Norris Cancer Center | Los Angeles | California | 90033 | — |
| Stanford University Medical Center | Palo Alto | California | 94304 | — |
| University Of Colorado | Aurora | Colorado | 80045 | — |
| The Urology Center of Colorado | Denver | Colorado | 80211 | — |
| Yale Cancer Center; Medical Oncology | New Haven | Connecticut | 06520 | — |
| Northwestern University Feinberg School Of Medicine | Chicago | Illinois | 60611 | — |
| University of Chicago; Hematology/Oncology | Chicago | Illinois | 60637 | — |
| University of Iowa Hospital & Clinic; Division of Hematology/Oncology | Iowa City | Iowa | 52242 | — |
| Albert B. Chandler Medical Center; University of Kentucky | Lexington | Kentucky | 40536 | — |
| Norton Cancer Institute | Louisville | Kentucky | 40202 | — |
| Johns Hopkins Sidney Kimmel Comprehensive Cancer Center | Baltimore | Maryland | 21287 | — |
| Chesapeake Urology Research Associates | Towson | Maryland | 21204 | — |
| Dana Farber Cancer Inst. | Boston | Massachusetts | 02115 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Massachusetts General Hospital. | Boston | Massachusetts | 2114 | — |
| University Of Michigan | Ann Arbor | Michigan | 48109 | — |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| MSK @Basking Ridge | Basking Ridge | New Jersey | 07920 | — |
| Saint Barnabas Medical Center Cancer Center | Livingston | New Jersey | 07039 | — |
| Memorial Sloan-Kettering Cancer Center | Commack | New York | 11725 | — |
| Laura and ISAAC Perlmutter Cancer Center at NYU Langone. | New York | New York | 10016 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Levine Cancer Institute | Charlotte | North Carolina | 28204 | — |
| Duke Cancer Center | Durham | North Carolina | 27710 | — |
| Wake Forest University Baptist Medical Center | Winston-Salem | North Carolina | 27157 | — |
| Cleveland Clinic | Cleveland | Ohio | 44106 | — |
| Fairview Hospital; Cleveland Clinic Cancer Center | Cleveland | Ohio | 44111 | — |
| The Ohio State University Wexner Medical Center | Columbus | Ohio | 43212 | — |
| Cleveland CL N Coast Cancer Cr | Sandusky | Ohio | 44870 | — |
| Abramson Cancer Center; Univ of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Kimmel Cancer Center Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Fox Chase-Temple Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Miriam Hospital | Providence | Rhode Island | 02906 | — |
| University of Texas Southwestern | Dallas | Texas | 75390-8897 | — |
| Baylor College of Medicine; Gastroenterology | Houston | Texas | 77030 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | — |
| University of Virginia | Charlottesville | Virginia | 22906 | — |
| Seattle Cancer Care Alliance | Seattle | Washington | 98109 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 145 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02450331, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 17, 2023 · Synced May 4, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02450331 live on ClinicalTrials.gov.