Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections
Public ClinicalTrials.gov record NCT02469857. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase III, Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Study of AB103 as Compared to Placebo in Patients With Necrotizing Soft Tissue Infections. ACCUTE (AB103 Clinical Composite Endpoint Study in Necrotizing Soft Tissue Infections)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether AB103 is safe and effective in the treatment of patients with necrotizing soft tissue infections (NSTI) receiving standard of care therapy.
Study identification
- NCT ID
- NCT02469857
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 290 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 1, 2015 (Actual)
- Primary completion
- Aug 18, 2019 (Actual)
- Completion
- Oct 18, 2019 (Actual)
- Last update posted
- Oct 5, 2021
2015 – 2019
United States locations
- U.S. sites
- 61
- U.S. states
- 28
- U.S. cities
- 54
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Maricopa Medical Center | Phoenix | Arizona | 85008 | — |
| Banner University Medical Center | Tucson | Arizona | 24857 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Loma Linda University Medical Center | Loma Linda | California | 92354 | — |
| Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center | Los Angeles | California | 90502 | — |
| University of California, Davis Medical Center | Sacramento | California | 95817 | — |
| UCSD Medical Center | San Diego | California | 92103 | — |
| UCH-Memorial Health System | Colorado Springs | Colorado | 80909 | — |
| University of Colorado Hospital | Denver | Colorado | 80045 | — |
| Yale New Haven Hospital | New Haven | Connecticut | 06520 | — |
| Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| UF Health Shands Hospital | Gainesville | Florida | 32610 | — |
| Ryder Trauma Center/Jackson Memorial Hospital | Miami | Florida | 33136 | — |
| Emory University at Grady Memorial Hospital | Atlanta | Georgia | 30303 | — |
| Augusta University Health | Augusta | Georgia | 30912 | — |
| University of Iowa Hospital and Clinics | Iowa City | Iowa | 52242 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Our Lady of the Lake Regional Medical Center | Baton Rouge | Louisiana | 70808 | — |
| Baton Rouge General Hospital | Baton Rouge | Louisiana | 70809 | — |
| LSU Health Science Center | New Orleans | Louisiana | 70112 | — |
| Maine Medical Center | Portland | Maine | 04102 | — |
| University of Maryland R Adams Cowley Shock Trauma Center | Baltimore | Maryland | 21201 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Wayne State University-Detroit Receiving Hospital | Detroit | Michigan | 48201 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Wayne State University-Sinai Grace Hospital | Detroit | Michigan | 48235 | — |
| Fairview Southdale Hospital | Edina | Minnesota | 55435 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55415 | — |
| University of Minnesota Medical Center-Fairview | Minneapolis | Minnesota | 55455 | — |
| University of Missouri | Columbia | Missouri | 65211 | — |
| St Louis University | St Louis | Missouri | 63103 | — |
| Cooper University Hospital | Camden | New Jersey | 08103 | — |
| Capital Health System, Inc. | Trenton | New Jersey | 98638 | — |
| Albany Medical Center | Albany | New York | 12208 | — |
| Erie County Medical Center-Affliate of SUNYat Buffalo | Buffalo | New York | 14215 | — |
| Staten Island University Hospital-Northwell Health | Staten Island | New York | 10305 | — |
| Carolinas Medical Center | Charlotte | North Carolina | 28208 | — |
| East Carolina University | Greenville | North Carolina | 27834 | — |
| University of Cincinnati Medical Center (UCMC) | Cincinnati | Ohio | 45219 | — |
| The MetroHealth System | Cleveland | Ohio | 44109 | — |
| The Ohio State University | Columbus | Ohio | 43210 | — |
| Wright State University & Premier Health Clinical Trials Research Alliance | Dayton | Ohio | 45409 | — |
| St Elizabeth Youngstown Hospital | Youngstown | Ohio | 44501 | — |
| Legacy Emanuel Hospital | Portland | Oregon | 97227 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| St. Luke's University Health Network | Bethlehem | Pennsylvania | 18015 | — |
| The Pennsylvania State University and The Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| The Trauma Center at PENN | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Texas Tech University Health Sciences Center at El Paso | El Paso | Texas | 79905 | — |
| John Peter Smith Health Network | Fort Worth | Texas | 76104 | — |
| Baylor College of Medicine-Ben Taub Hospital | Houston | Texas | 77030 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | — |
| Scott and White Medical Center | Temple | Texas | 76502 | — |
| Harborview Medical Center | Seattle | Washington | 98104 | — |
| Medical College of Wisconsin-Froedtert Hospital | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02469857, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 5, 2021 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02469857 live on ClinicalTrials.gov.