Study of Acalabrutinib (ACP-196) Versus Ibrutinib in Previously Treated Participants With High Risk Chronic Lymphocytic Leukemia (CLL)
Public ClinicalTrials.gov record NCT02477696. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Multicenter, Open-Label, Non-Inferiority, Phase III Study of Acalabrutinib (ACP-196) Versus Ibrutinib in Previously Treated Subjects With High Risk Chronic Lymphocytic Leukemia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is designed to evaluate progression-free survival (PFS) endpoint for acalabrutinib versus (vs) ibrutinib in previously treated chronic lymphocytic leukemia.
Study identification
- NCT ID
- NCT02477696
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 533 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 28, 2015 (Actual)
- Primary completion
- Sep 15, 2020 (Actual)
- Completion
- Jan 3, 2028 (Estimated)
- Last update posted
- Aug 26, 2026
2015 – 2028
United States locations
- U.S. sites
- 31
- U.S. states
- 17
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Phoenix | Arizona | 85054 | — |
| Research Site | Anaheim | California | 92801 | — |
| Research Site | Berkeley | California | 94704 | — |
| Research Site | Duarte | California | 91010 | — |
| Research Site | La Jolla | California | 92093 | — |
| Research Site | Los Angeles | California | 90095 | — |
| Research Site | Palo Alto | California | 94304 | — |
| Research Site | Santa Rosa | California | 95403 | — |
| Research Site | Jacksonville | Florida | 32224 | — |
| Research Site | Tampa | Florida | 33612 | — |
| Research Site | Athens | Georgia | 30607 | — |
| Research Site | Harvey | Illinois | 60426 | — |
| Research Site | Peoria | Illinois | 61615 | — |
| Research Site | Wichita | Kansas | 67214 | — |
| Research Site | Minneapolis | Minnesota | 55426 | — |
| Research Site | Rochester | Minnesota | 55905 | — |
| Research Site | Billings | Montana | 59102 | — |
| Research Site | Hackensack | New Jersey | ?07601 | — |
| Research Site | Lake Success | New York | 11042 | — |
| Research Site | New Hyde Park | New York | 11042 | — |
| Research Site | New York | New York | 10021 | — |
| Research Site | New York | New York | 10029 | — |
| Research Site | New York | New York | 10065 | — |
| Research Site | Durham | North Carolina | 27710 | — |
| Research Site | Columbus | Ohio | 43210 | — |
| Research Site | Philadelphia | Pennsylvania | 19104 | — |
| Research Site | Houston | Texas | 77030 | — |
| Research Site | Round Rock | Texas | 78665 | — |
| Research Site | Charlottesville | Virginia | 22908 | — |
| Research Site | Tacoma | Washington | 98405 | — |
| Research Site | Northwest WA | Wisconsin | 20007 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 99 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02477696, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 26, 2026 · Synced Oct 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02477696 live on ClinicalTrials.gov.