ClinicalTrials.gov record
Active, not recruiting Phase 3 Interventional Results available

A Study of Apalutamide (JNJ-56021927, ARN-509) Plus Androgen Deprivation Therapy (ADT) Versus ADT in Participants With mHSPC

ClinicalTrials.gov ID: NCT02489318

Public ClinicalTrials.gov record NCT02489318. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 6, 2026, 8:15 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3 Randomized, Placebo-controlled, Double-blind Study of Apalutamide Plus Androgen Deprivation Therapy (ADT) Versus ADT in Subjects With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

Study identification

NCT ID
NCT02489318
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Aragon Pharmaceuticals, Inc.
Industry
Enrollment
1,052 participants

Conditions and interventions

Interventions

  • Androgen Deprivation Therapy (ADT) Drug
  • Apalutamide Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
Male
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 26, 2015
Primary completion
Sep 6, 2020
Completion
Dec 30, 2027
Last update posted
Apr 12, 2026

2015 – 2027

United States locations

U.S. sites
39
U.S. states
24
U.S. cities
39
Facility City State ZIP Site status
Not listed Homewood Alabama
Not listed Tucson Arizona
Not listed San Bernardino California
Not listed San Diego California
Not listed Denver Colorado
Not listed Norwalk Connecticut
Not listed Fort Myers Florida
Not listed Chicago Illinois
Not listed Fort Wayne Indiana
Not listed Jeffersonville Indiana
Not listed New Orleans Louisiana
Not listed Baltimore Maryland
Not listed Rockville Maryland
Not listed Lansing Michigan
Not listed Troy Michigan
Not listed Omaha Nebraska
Not listed Las Vegas Nevada
Not listed Brooklyn New York
Not listed Poughkeepsie New York
Not listed Syracuse New York
Not listed The Bronx New York
Not listed Raleigh North Carolina
Not listed Salisbury North Carolina
Not listed Cleveland Ohio
Not listed Middleburg Heights Ohio
Not listed Springfield Oregon
Not listed Bala-Cynwyd Pennsylvania
Not listed Bryn Mawr Pennsylvania
Not listed Lancaster Pennsylvania
Not listed Charleston South Carolina
Not listed Nashville Tennessee
Not listed Dallas Texas
Not listed Houston Texas
Not listed San Antonio Texas
Not listed Richmond Virginia
Not listed Virginia Beach Virginia
Not listed Burien Washington
Not listed Spokane Washington
Not listed Milwaukee Wisconsin

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 181 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02489318, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 12, 2026 · Synced May 6, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02489318 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →