RRx-001 in Lung Cancer, Ovarian Cancer and Neuroendocrine Tumors Prior to Re-administration of Platinum Based Doublet Regimens (QUADRUPLE THREAT)
Public ClinicalTrials.gov record NCT02489903. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Study of RRx-001 in Platinum Refractory/Resistant Small Cell Carcinoma, EGFR TKI Resistant EGFR+ T790M Negative Non-Small Cell Lung Cancer, High Grade Neuroendocrine Tumors and Resistant/Refractory Ovarian Cancer Prior to Re-administration of Platinum Based Doublet Regimens (QUADRUPLE THREAT)
Study identification
- NCT ID
- NCT02489903
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- EpicentRx, Inc.
- Industry
- Enrollment
- 139 participants
Conditions and interventions
Conditions
Interventions
- Carboplatin Drug
- Cisplatin Drug
- Doxil Drug
- Etoposide Drug
- Gemcitabine Drug
- Irinotecan Drug
- Nab-Paclitaxel Drug
- Paclitaxel Drug
- Pemetrexed Drug
- RRx-001 Drug
- Taxane Drug
- Vinorelbine Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2015
- Primary completion
- Dec 5, 2021
- Completion
- Dec 5, 2021
- Last update posted
- Mar 16, 2025
2015 – 2021
United States locations
- U.S. sites
- 10
- U.S. states
- 10
- U.S. cities
- 10
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Stanford University | Palo Alto | California | 94304 | — |
| VA Connecticut Cancer Center | West Haven | Connecticut | 06516 | — |
| Memorial Hospital of South Bend | South Bend | Indiana | 46601 | — |
| Baptist Health | Lexington | Kentucky | 40503 | — |
| Walter Reed National Military Medical Center | Bethesda | Maryland | 20889 | — |
| Henry Ford Allegiance Health | Jackson | Michigan | 49201 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| University of Cincinnati Cancer Institute | Cincinnati | Ohio | 45267 | — |
| Virginia Cancer Specialists | Fairfax | Virginia | 22031 | — |
| West Virginia University | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02489903, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 16, 2025 · Synced May 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02489903 live on ClinicalTrials.gov.