ClinicalTrials.gov record
Not listed Phase 3 Interventional

CREATE-1: A Study to Assess the Efficacy and Safety of AXS-02 in Patients With CRPS-1

ClinicalTrials.gov ID: NCT02504008

Public ClinicalTrials.gov record NCT02504008. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 22, 2026, 11:18 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

CREATE-1 Study: CRPS Treatment Evaluation 1 Study. A Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy and Safety of AXS-02 (Oral Zoledronate) Administered Orally to Subjects With Complex Regional Pain Syndrome Type I (CRPS-I)

Study identification

NCT ID
NCT02504008
Recruitment status
Not listed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Axsome Therapeutics, Inc.
Industry
Enrollment
190 participants

Conditions and interventions

Interventions

  • AXS-02 (oral zoledronate) Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Not listed

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 30, 2015
Primary completion
Dec 31, 2018
Completion
Dec 31, 2018
Last update posted
Mar 22, 2018

2015 – 2019

United States locations

U.S. sites
29
U.S. states
17
U.S. cities
29
Facility City State ZIP Site status
Not listed Tucson Arizona
Not listed Hot Springs Arkansas
Not listed Encinitas California
Not listed La Jolla California
Not listed Los Angeles California
Not listed Napa California
Not listed Temecula California
Not listed Denver Colorado
Not listed Clermont Florida
Not listed Miami Florida
Not listed Orlando Florida 32827
Not listed Tampa Florida
Not listed West Palm Beach Florida
Not listed Canton Georgia
Not listed Marietta Georgia
Not listed St. Marys Georgia 31558
Not listed Meridian Idaho
Not listed Chicago Illinois
Not listed Louisville Kentucky
Not listed Albuquerque New Mexico
Not listed New York New York
Not listed Winston-Salem North Carolina
Not listed Oklahoma City Oklahoma
Not listed Portland Oregon
Not listed Dallas Texas
Not listed San Antonio Texas
Not listed Bellevue Washington
Not listed Seattle Washington
Not listed Madison Wisconsin

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02504008, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 22, 2018 · Synced Apr 22, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02504008 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →