Andecaliximab With mFOLFOX6 as First Line Treatment for Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
Public ClinicalTrials.gov record NCT02545504. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of GS-5745 Combined With mFOLFOX6 as First Line Treatment in Patients With Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to compare the efficacy of andecaliximab (GS-5745) versus placebo in combination with modified fluorouracil (5-FU), leucovorin (LV), and oxaliplatin (OXA) (mFOLFOX6) as measured by overall survival.
Study identification
- NCT ID
- NCT02545504
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 432 participants
Conditions and interventions
Conditions
Interventions
- Andecaliximab Drug
- Placebo Drug
- Leucovorin Drug
- 5-fluorouracil Drug
- Oxaliplatin Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 13, 2015 (Actual)
- Primary completion
- May 15, 2019 (Actual)
- Completion
- May 15, 2019 (Actual)
- Last update posted
- May 26, 2020
2015 – 2019
United States locations
- U.S. sites
- 31
- U.S. states
- 21
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Scripps Green Hospital | La Jolla | California | 92037 | — |
| University of Southern California | Los Angeles | California | 90007 | — |
| UCLA Jonsson Comprehensive Cancer Center | Los Angeles | California | 90024 | — |
| Innovative Clinical Research Institute | Whittier | California | 90603 | — |
| Cancer Center of Central Connecticut | Plainville | Connecticut | 06062 | — |
| Omega Research Consultants LLC | DeBary | Florida | 32713 | — |
| Edward Hospital & Health Services | Naperville | Illinois | 60540 | — |
| Parkview Hospital | Fort Wayne | Indiana | 46805 | — |
| Indiana University Goshen Center for Cancer Care | Goshen | Indiana | 46526 | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70816 | — |
| New England Cancer Specialists | Scarborough | Maine | 04074 | — |
| Karamanos Cancer Institute | Detroit | Michigan | 48175 | — |
| HCA Healthcare | Kansas City | Missouri | 64030 | — |
| Carol G. Simon Cancer Center | Morristown | New Jersey | 07901 | — |
| Regional Cancer Care Associates LLC - Sparta | Sparta | New Jersey | 07871 | — |
| Weill Cornell Medical College - New York Presbyterian Hospital | New York | New York | 10065 | — |
| University of Rochester | Rochester | New York | 14627 | — |
| Duke Cancer Institute | Durham | North Carolina | 27710 | — |
| Oncology Hematology Care, Inc. | Cincinnati | Ohio | 45242 | — |
| The Ohio State Medical Center | Columbus | Ohio | 43210 | — |
| Northwest Cancer Specialists | Portland | Oregon | 97213 | — |
| Charleston Hematology Oncology Associates | Charleston | South Carolina | 29403 | — |
| Prairie Lakes Health Care System INC | Watertown | South Dakota | — | — |
| Tennessee Oncology | Nashville | Tennessee | — | — |
| Center for Cancer Blood Disorders | Fort Worth | Texas | — | — |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | — | — |
| Texas Oncology-Seton Williamson | Round Rock | Texas | — | — |
| Scott and White Memorial Hospital | Temple | Texas | — | — |
| Utah Cancer Specialists | Salt Lake City | Utah | — | — |
| Virginia Commonwealth University | Richmond | Virginia | — | — |
| Virginia Mason Seattle Main Clinic | Seattle | Washington | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 103 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02545504, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 26, 2020 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02545504 live on ClinicalTrials.gov.