A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease
Public ClinicalTrials.gov record NCT02565511. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Two-cohort, Parallel Group Study to Evaluate the Efficacy of CAD106 and CNP520 in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study was to test whether two investigational drugs called CAD106 and CNP520, administered separately, could slow down the onset and progression of clinical symptoms associated with Alzheimer's disease (AD) in participants at the risk to develop clinical symptoms based on their age and genotype.
Study identification
- NCT ID
- NCT02565511
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 480 participants
Conditions and interventions
Conditions
Interventions
- CAD106 Immunotherapy Biological
- Placebo to CAD106 Other
- CNP520 Drug
- Placebo to CNP520 Other
- Alum Other
Biological · Other · Drug
Eligibility (public fields only)
- Age range
- 60 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 30, 2015 (Actual)
- Primary completion
- Apr 30, 2020 (Actual)
- Completion
- Apr 30, 2020 (Actual)
- Last update posted
- Jul 8, 2021
2015 – 2020
United States locations
- U.S. sites
- 78
- U.S. states
- 33
- U.S. cities
- 70
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner Alzheimer's Institute | Phoenix | Arizona | 85006 | — |
| Novartis Investigative Site | Phoenix | Arizona | 85006 | — |
| Novartis Investigative Site | Scottsdale | Arizona | 85259 | — |
| Banner Sun City Research Institute | Sun City | Arizona | 85351 | — |
| ATP Clinical Research, Inc. | Costa Mesa | California | 92626 | — |
| Irvine Center for Clinical Research | Irvine | California | 92614 | — |
| University of Southern California Keck School of Medicine Alzheimer Disease Research Center | Los Angeles | California | 90033 | — |
| Novartis Investigative Site | Palo Alto | California | 94304 | — |
| Novartis Investigative Site | San Diego | California | 92103 | — |
| Syrentis Clinical Research | Santa Ana | California | 92705 | — |
| Novartis Investigative Site | Sebastopol | California | 95472 | — |
| California Neuroscience Research Medical Group, Inc. | Sherman Oaks | California | 91316 | — |
| Novartis Investigative Site | Temecula | California | 92591 | — |
| Novartis Investigative Site | Basalt | Colorado | 81621 | — |
| Yale University Alzheimer's Disease Research Unit | New Haven | Connecticut | 06510 | — |
| New England Institute for Clinical Research | Stamford | Connecticut | 06905 | — |
| Georgetown University | Washington D.C. | District of Columbia | 20057 | — |
| Novartis Investigative Site | Washington D.C. | District of Columbia | 20059 | — |
| JEM Research Institute | Atlantis | Florida | 33462-6608 | — |
| Florida Atlantic University, Clinical Translational Research Unit | Boca Raton | Florida | 33431 | — |
| Brain Matters Research | Delray Beach | Florida | 33445 | — |
| Novartis Investigative Site | Jacksonville | Florida | 32224 | — |
| Meridien Research | Maitland | Florida | 32751 | — |
| Merritt Island Medical Research | Merritt Island | Florida | 32952 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Mount Sinai Medical Center - The Wien Center | Miami Beach | Florida | 33140 | — |
| Novartis Investigative Site | Orlando | Florida | 32806 | — |
| Compass Research | Orlando | Florida | 32812 | — |
| Progressive Medical Research | Port Orange | Florida | 32127 | — |
| USF Health Byrd Alzheimer's Institute | Tampa | Florida | 33613 | — |
| Novartis Investigative Site | Atlanta | Georgia | 30322 | — |
| Medical Research & Health Education Foundation, Inc. | Columbus | Georgia | 31909 | — |
| NeuroStudies | Decatur | Georgia | 30033 | — |
| Advanced Clinical Research | Meridian | Idaho | 83642 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Great Lakes Clinical Trials | Chicago | Illinois | 60640 | — |
| Indiana University | Indianapolis | Indiana | 46202 | — |
| University of Kansas Alzheimer's Disease Center | Fairway | Kansas | 66205 | — |
| Via Christi Research | Wichita | Kansas | 67214 | — |
| Sanders Brown Center on Aging, University of Kentucky | Lexington | Kentucky | 40504 | — |
| Novartis Investigative Site | Bangor | Maine | 04401 | — |
| Novartis Investigative Site | Boston | Massachusetts | 02115 | — |
| Novartis Investigative Site | Boston | Massachusetts | 02118 | — |
| Novartis Investigative Site | Kalamazoo | Michigan | 49008 | — |
| Novartis Investigative Site | Saint Paul | Minnesota | 55130 | — |
| Novartis Investigative Site | St Louis | Missouri | 63104 | — |
| Memory Disorders Program, Department of Neurological Sciences, University of Nebraska Medical Center | Omaha | Nebraska | 68198-7680 | — |
| Cleveland Clinic Lou Ruvo Center for Brain Health | Las Vegas | Nevada | 89106 | — |
| Memory Enhancement Center | Eatontown | New Jersey | 07724 | — |
| The Memory Center of Northeastern New York | Latham | New York | 12110 | — |
| NYU Langone Medical Center | New York | New York | 10016 | — |
| The Nathan S. Kline Institute | Orangeburg | New York | 10962 | — |
| University of Rochester Medical Center | Rochester | New York | 14620 | — |
| Alzheimer's Memory Center | Charlotte | North Carolina | 28270 | — |
| Duke University Medical center | Durham | North Carolina | 27705 | — |
| Triad Clinical Trials, LLC | Greensboro | North Carolina | 27410 | — |
| University Hospitals Cleveland Medical Center / Case Western Reserve University | Beachwood | Ohio | 44122 | — |
| Novartis Investigative Site | Centerville | Ohio | 45459 | — |
| Novartis Investigative Site | Columbus | Ohio | 43210 | — |
| IPS Research Company | Oklahoma City | Oklahoma | 73103 | — |
| Novartis Investigative Site | Oklahoma City | Oklahoma | 73112 | — |
| Memory Health Center at Summit Research Network | Portland | Oregon | 97210 | — |
| The Clinical Trial Center, LLC | Jenkintown | Pennsylvania | 19046 | — |
| Novartis Investigative Site | Philadelphia | Pennsylvania | 19104 | — |
| Abington Neurological Associates | Willow Grove | Pennsylvania | 19090 | — |
| Butler Hospital Memory and Aging Program | Providence | Rhode Island | 02906 | — |
| Roper St. Francis - CBRI | Charleston | South Carolina | 29401 | — |
| Novartis Investigative Site | Knoxville | Tennessee | 37920 | — |
| CNS Healthcare | Memphis | Tennessee | 38119 | — |
| Novartis Investigative Site | Nashville | Tennessee | 37212 | — |
| Senior Adults Specialty Research | Austin | Texas | 78757 | — |
| Kerwin Research Center & Memory Care | Dallas | Texas | 75231 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| University of Texas Health Science Center, Houston | Houston | Texas | 77054 | — |
| Clinical Trial Network | Houston | Texas | 77074 | — |
| The Memory Clinic | Bennington | Vermont | 05201 | — |
| Universal Research Group | Tacoma | Washington | 98405 | — |
| The Medical College of WI | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 51 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02565511, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 8, 2021 · Synced Oct 29, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02565511 live on ClinicalTrials.gov.