ClinicalTrials.gov record
Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)
ClinicalTrials.gov ID: NCT02568267
Public ClinicalTrials.gov record NCT02568267. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 10, 2026, 5:59 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label, Multicenter, Global Phase 2 Basket Study of Entrectinib for the Treatment of Patients With Locally Advanced or Metastatic Solid Tumors That Harbor NTRK1/2/3, ROS1, or ALK Gene Rearrangements
Study identification
- NCT ID
- NCT02568267
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 534 participants
Conditions and interventions
Conditions
- Adult Solid Tumor
- Breast Cancer
- Cholangiocarcinoma
- Colorectal Cancer
- Head and Neck Neoplasms
- Lymphoma, Large-Cell, Anaplastic
- Melanoma
- Neuroendocrine Tumors
- Non-Small Cell Lung Cancer
- Ovarian Cancer
- Pancreatic Cancer
- Papillary Thyroid Cancer
- Primary Brain Tumors
- Renal Cell Carcinoma
- Salivary Gland Cancers
- Sarcomas
Interventions
- Entrectinib Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 18, 2015
- Primary completion
- May 13, 2026
- Completion
- May 13, 2026
- Last update posted
- Mar 5, 2026
2015 – 2026
United States locations
- U.S. sites
- 53
- U.S. states
- 23
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Dignity Health St Joseph's Hospital and Medical Center | Phoenix | Arizona | 85013 | — |
| Mayo Clinic | Phoenix | Arizona | 85054 | — |
| City of Hope Cancer Center | Duarte | California | 91010 | — |
| City of Hope Duarte - Comprehensive Cancer Center, Investigational Drug Services | Duarte | California | 91010 | — |
| Scripps Clinic | La Jolla | California | 92037 | — |
| University of California San Diego Moores Cancer Center | La Jolla | California | 92093 | — |
| Southern California Kaiser Permanente | Los Angeles | California | 90027 | — |
| University of Southern California Medical Center | Los Angeles | California | 90032 | — |
| Univ Of California Irvine College Of Medicine | Orange | California | 92868 | — |
| UCSF Mount Zion Medical Ctr | San Francisco | California | 94115 | — |
| UCSF Mission Bay | San Francisco | California | 94158 | — |
| Sarcoma Oncology Center | Santa Monica | California | 90403 | — |
| Sarcoma Oncology Research Center LLC | Santa Monica | California | 90403 | — |
| University of Colorado Cancer Center | Aurora | Colorado | 80045 | — |
| Yale University | New Haven | Connecticut | 6519 | — |
| Georgetown University Medical Center Lombardi Cancer Center | Washington D.C. | District of Columbia | 20007 | — |
| Florida Cancer Specialists - Sarasota | Sarasota | Florida | 34232 | — |
| H. Lee Moffitt Cancer Center and Research Inst. | Tampa | Florida | 33612-9497 | — |
| Moffitt Cancer Center | Tampa | Florida | 33612-9497 | — |
| University Cancer & Blood Center, LLC | Athens | Georgia | 30607 | — |
| Winship Cancer Institute | Atlanta | Georgia | 30322 | — |
| Southeastern Regional Medical Center, Inc. | Newnan | Georgia | 30265 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Advocate Medical Group - Park Ridge, Luther Lane - Oncology | Park Ridge | Illinois | 60068 | — |
| Midwestern Regional Medical Center | Zion | Illinois | 60099 | — |
| Weinberg Cancer Institution at Franklin Square | Baltimore | Maryland | 21237 | — |
| Massachusetts General Hosp CAR | Boston | Massachusetts | 02114 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109 | — |
| Karmanos Cancer Center | Detroit | Michigan | 48201 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Regents of the University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Washington University | St Louis | Missouri | 63128 | — |
| Comprehensive Cancer Centers of Nevada (CCCN) - Central Valley | Las Vegas | Nevada | 89169 | — |
| North Shore Hem Onc Associates | East Setauket | New York | 11733 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10022 | — |
| Atrium Health Levine Cancer Institute | Charlotte | North Carolina | 28204 | — |
| Levine Cancer Institute | Charlotte | North Carolina | 28204 | — |
| Duke Cancer Institute | Durham | North Carolina | 27710 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| OSU, James Cancer Hospital | Columbus | Ohio | 43210 | — |
| Cancer Treatment Centers of America | Tulsa | Oklahoma | 74133 | — |
| Oregon Health & Science University | Portland | Oregon | 97239-3098 | — |
| Oregon Health & Science Univ | Portland | Oregon | 97239 | — |
| Mary Crowley Medical Research Center | Dallas | Texas | 75230 | — |
| University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Baylor Scott & White Health | Temple | Texas | 76508 | — |
| University of Utah Hospitals & Clinics | Salt Lake City | Utah | 84112 | — |
| Virginia Cancer Specialists, PC | Fairfax | Virginia | 22031 | — |
| Virginia Oncology Associates - Hampton | Norfolk | Virginia | 23502 | — |
| University of Washington Seattle Cancer Care Alliance | Seattle | Washington | 98109 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 77 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02568267, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 5, 2026 · Synced May 10, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02568267 live on ClinicalTrials.gov.